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Urethral duplication with five openings in anal canal: A novel case report.
Indian J Urol
January 2025
Department of Paediatric Surgery, AIIMS, New Delhi, India.
Urethral duplication is a rare congenital anomaly characterized by more than one urethral channel, with varied course, location of the external opening, and presentation. Presentations can be varied, depending upon individual anatomical dispensation but mostly present as obstruction, recurrent urinary infection, or double urinary stream. Treatment depends on the type of duplication and associated anomalies.
View Article and Find Full Text PDFDevelopment of machine learning-based models for vault prediction in implantable collamer lens surgery according to implant orientation.
J Cataract Refract Surg
January 2025
Department of Anterior Segment, Cornea and Refractive Surgery, Hospital Arruzafa, Cordoba, Spain.
Purpose: The main objective was to develop a prediction model based on machine learning to calculate the postoperative vault as well as the ideal implantable collamer lens (ICL) size, considering for the first time the implantation orientation in a Caucasian population.
Setting: Arruzafa Ophthalmological Hospital (Cordoba, Spain) and Barraquer Ophthalmology Center (Barcelona, Spain).
Design: Multicenter, randomized, retrospective study.
How effective and sustainable is proctoring in robotic surgery? A retrospective analysis based on interviews with surgeons.
Surg Endosc
January 2025
Department of Obstetrics and Gynecology, University Hospitals Schleswig-Holstein, Campus Kiel, Arnold-Heller-Strasse 3 (House C), 24105, Kiel, Germany.
Background: Robot-assisted surgery is one of several minimally invasive techniques which have become increasingly important in recent years. Education and training are key factors of sustainable success, and surgical tutoring by an experienced external surgeon (proctoring) has emerged as a very useful method of training surgeons. Proctoring enables surgeons to train their respective skills and eventually improve the overall quality of surgical care.
View Article and Find Full Text PDFAssessing the Utilization of HIV Genotype Resistance Testing: Insight from Italian Infectious Diseases Units.
J Glob Antimicrob Resist
January 2025
Infectious Diseases Unit, Legnano General Hospital, ASST Ovest Milanese, Legnano (MI), and DIBIC, University of Milan, Italy.
Purpose: We aimed to assess the utilization of Genotype Resistance Testing (GRT) by Infectious Diseases Units across Italy.
Methods: A cross-sectional study was conducted involving a questionnaire distributed to the Infectious Diseases Unit in Italy. A web-based survey using Google Forms software was utilized and spread via email or cellphone.
Uterine organoids reveal insights into epithelial specification and plasticity in development and disease.
Proc Natl Acad Sci U S A
February 2025
Department of Obstetrics, Gynecology, and Women's Health, University of Missouri, Columbia, MO 65211.
Understanding how epithelial cells in the female reproductive tract (FRT) differentiate is crucial for reproductive health, yet the underlying mechanisms remain poorly defined. At birth, FRT epithelium is highly malleable, allowing differentiation into various epithelial types, but the regulatory pathways guiding these early cell fate decisions are unclear. Here, we use neonatal mouse endometrial organoids and assembloid coculture models to investigate how innate cellular plasticity and external mesenchymal signals influence epithelial differentiation.
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