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Osteoporosis in rheumatoid arthritis.

Rev Med Chir Soc Med Nat Iasi

March 2014

Department of School Health, Faculty of Medicine, University of Medicine and Pharmacy, "Grigore T. Popa" - Iaşi.

Unlabelled: Osteoporosis (OP) is a disease of great medical and social importance and it is reported frequently and precociously in rheumatoid arthritis (RA) patients.

Material And Methods: A retrospective study was conducted on a random sample of 180 patients admitted in the period 2011-2012 to the Rheumatology Clinic of the lasi Rehabilitation Hospital. The patients were diagnosed with RA and osteoporosis and some clinical and biological parameters were analyzed.

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Travels and travails of autoimmunity: a historical journey from discovery to rediscovery.

Autoimmun Rev

March 2010

Department of Biochemistry & Molecular Biology, Monash University, Clayton, Victoria 3800, Australia.

Consideration on autoimmunity began, as did immunology itself, around year 1900, first with Ehrlich's doctrine of 'horror autotoxicus', then interpreted as 'autoimmunity cannot happen'. Yet by 1904 the antibody nature of the autohemolysin responsible for cold hemoglobinuria was described, and soon confirmed, but without generating any durable concept on autoimmunization as a cause of disease. Reasons included Ehrlich's doctrine, the particular directions that immunology was to take after the initial advances, and a greater preoccupation with bodily responses to extrinsic rather than autologous substances.

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Objectives: To look for possible regional differences in the prevalence of rheumatoid factor (RF) in the presence and absence of arthritis.

Methods: The study covered a representative sample of the Finnish population aged 30 years or over, primarily comprising 8000 people, of whom 7217 participated in the field survey carried out in 1978-80. RF from serum samples from 7116 subjects was determined by the Waaler-Rose (sensitised sheep cell agglutination) test.

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Exposure to silica minerals is associated with silicosis and autoimmune disorders, especially systemic scleroderma. Evidence of this association has been increasingly reported in the last decade. The aim of this paper is to discuss, on the basis of a literature review, the case of a 28-year-old female dental technician who suffered from episodes of weakness, arthralgia, pain, swelling and stiffness of the fingers, dyspnoea with cough, a positive Waaler-Rose reaction, increased rheumatoid factor and normal ESR.

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[Incidence of osteoporosis in patients with rheumatoid arthritis].

Przegl Lek

October 2000

Oddział Reumatologiczny Wojewódzkiego Szpitala Podkarpackiego im. Jana Pawła II w Krośnie.

Juxta-articular osteoporosis in rheumatoid arthritis (RA) is an early and specific pathology in this disease, however in RA patients there are also factors predisposing for the development of the generalised bone atrophy. 103 female patients with the diagnosis of RA established according to ACR criteria were included in the study. Its aim was to evaluate the generalised osteoporosis incidence in women suffering from RA as well as to find out how osteoporosis was related to certain clinical symptoms and laboratory findings, the disease process activity, and the treatment used.

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