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Volatiles extracted from Melaleuca Rugulosa (Link) Craven leaves: comparative profiling, bioactivity screening, and metabolomic analysis.
BMC Complement Med Ther
November 2024
Department of Pharmacognosy, Faculty of Pharmacy, Helwan University, Cairo, 11795, Egypt.
Background: Melaleuca species (family Myrtaceae) are characterized by their wide-ranging applications as antimicrobials and in skin-related conditions. Herein, we estimated the volatile profile and biological significance of M. rugulosa (Link) leaves for the first time supported by a dereplication protocol.
View Article and Find Full Text PDFAlpinia officinarum Hance Essential Oil as Potent Antipseudomonal Agent: Chemical Profile, Antibacterial Activity, and Computational Study.
Chem Biodivers
October 2024
Laboratory of Drugs Sciences, Biomedical Research and Biotechnology, Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P. 9154, Casablanca, 20250, Morocco.
Article Synopsis
- - The study explores the antibacterial properties of the essential oil from the herb Alpinia officinarum, revealing that eucalyptol is its main component with potential antimicrobial effects.
- - It shows that the essential oil effectively inhibits the growth of harmful bacteria like Pseudomonas aeruginosa and Escherichia coli, outperforming standard antibiotics in some tests.
- - The research indicates that the compounds in the essential oil have good binding potential to bacterial targets and favorable pharmacokinetic and toxicity profiles, highlighting the need for alternatives to combat antibiotic resistance.
Lupin Seed Supplementation as a Functional Feed Additive: Ruminal Gas, Methane and Carbon Dioxide Production, Fermentation Kinetics, and Nutrient Degradability.
Animals (Basel)
July 2024
Department of Animal, Veterinary and Food Sciences, University of Idaho, 315 Falls Ave., Twin Falls, ID 83301, USA.
The inevitable enteric gas emission from ruminants is considered a modern-day problem from an environmental perspective. Addressing this problem requires nutritional approaches such as the use of phytogenic additives in ruminant diets. In this regard, lupin seed (LS) can be a useful additive due to its phytochemical constituents.
View Article and Find Full Text PDFThe Anticancer Activities of Natural Terpenoids That Inhibit Both Melanoma and Non-Melanoma Skin Cancers.
Int J Mol Sci
April 2024
Department of Food Bioscience and Technology, College of Life Sciences and Biotechnology, Korea University, Seoul 02855, Republic of Korea.
The prevalence of two major types of skin cancer, melanoma and non-melanoma skin cancer, has been increasing worldwide. Skin cancer incidence is estimated to rise continuously over the next 20 years due to ozone depletion and an increased life expectancy. Chemotherapeutic agents could affect healthy cells, and thus may be toxic to them and cause numerous side effects or drug resistance.
View Article and Find Full Text PDFPromising effects of 1,8 Cineole to control Giardia lamblia infection: Targeting the inflammation, oxidative stress, and infectivity.
Acta Trop
July 2024
Nutritional Health Research Center, Lorestan University of Medical Sciences, Khorramabad, Iran. Electronic address:
Reportedly, synthetic drugs such as metronidazole, furazolidone, tinidazole, and quinacrine are used for the treatment of giardiasis but are associated with adverse effects. In this study, we aimed to investigate the in vitro and in vivo effects of eucalyptol (ECT, 1,8 cineole) alone and in combination with metronidazole (MNZ) on Giardia lamblia. The effects of ECT on cell viability, plasma membrane permeability, and gene expression levels of adenylate cyclase (AK) and extracellular signal kinases 1 and 2 (ERK1 and ERK2) in trophozoites of G.
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