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Comparative analysis of biodiversity, physiology, and anatomical adaptations in riparian flora exposed to industrial pollution stress.
Sci Rep
January 2025
Department of Botany, Division of Science and Technology, University of Education, Lahore, Punjab, Pakistan.
Anthropogenic activities such as industrial pollution of water bodies possess threat to floras leading to extinction and endangerment. This study investigates the impact of industrial pollution on vegetation along River Chenab and its associated drains. Rivers and channels transporting industrial effluents have been determined to be significantly contaminated.
View Article and Find Full Text PDFRole of astrocytes connexins - pannexins in acute brain injury.
Neurotherapeutics
January 2025
Departamento de Medicina Intensiva, Facultad de Medicina, Pontificia Universidad Católica de Chile, Chile. Electronic address:
Acute brain injuries (ABIs) encompass a broad spectrum of primary injuries such as ischemia, hypoxia, trauma, and hemorrhage that converge into secondary injury where some mechanisms show common determinants. In this regard, astroglial connexin and pannexin channels have been shown to play an important role. These channels are transmembrane proteins sharing similar topology and form gateways between adjacent cells named gap junctions (GJs) and pores into unopposed membranes named hemichannels (HCs).
View Article and Find Full Text PDFScreening of Retinal-targeting Adeno-Associated Virus (AAV) via DNA shuffling.
Exp Eye Res
January 2025
Institutes of Biology and Medical Sciences, Soochow University, Suzhou, 215000, China; Key Laboratory of Geriatric Diseases and Immunology, Ministry of Education, Institutes of Biology and Medical Sciences, Suzhou Medical College of Soochow University, Suzhou 215123, China. Electronic address:
Due to its unique physiological structure and functions, the eye has received considerable attention in the field of Adeno-associated virus (AAV) gene therapy. Inherited retinal degenerative diseases, which arise from pathogenic mutations in mRNA transcripts expressed in the eye's photoreceptor cells or retinal pigment epithelium (RPE), are the most common cause of vision loss. However, current retinal gene therapy mostly involves subretinal injection of therapeutic genes, which treats a limited area, entails retinal detachment, and requires sophisticated techniques.
View Article and Find Full Text PDFToxicity mechanism of metal-organic framework HKUST-1 and its carbonized product to Tetradesmus obliquus: Physiological and transcriptomic analysis.
Comp Biochem Physiol C Toxicol Pharmacol
January 2025
School of Ecology and Environment, Collaborative Innovation Center of Recovery and Reconstruction of Degraded Ecosystem in Wanjiang Basin Co-founded by Anhui Province and Ministry of Education, Anhui Normal University, Wuhu 241002, China. Electronic address:
Metal-organic frameworks (MOFs) are emerging materials with unique structures and properties, which have been widely used in many fields due to their various advantages. However, compared with its popular application research, the ecological safety of MOFs has rarely been reported. In this paper, a biological model, the common freshwater green algae Tetradesmus obliquus (T.
View Article and Find Full Text PDFUncovering the chromatin-mediated transcriptional regulatory network governing cold stress responses in fish immune cells.
J Genet Genomics
January 2025
Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Ocean University, Shanghai 201306, China; International Research Center for Marine Biosciences, Ministry of Science and Technology, Shanghai Ocean University, Shanghai 201306, China; Marine Biomedical Science and Technology Innovation Platform of Lin-gang Special Area, Shanghai 201306, China. Electronic address:
Temperature fluctuations challenge ectothermic species, particularly tropical fish dependent on external temperatures for physiological regulation. However, the molecular mechanisms through which low-temperature stress impacts immune responses in these species, especially in relation to chromatin accessibility and epigenetic regulation, remain poorly understood. In this study, we investigate chromatin and transcriptional changes in the head kidney and thymus tissues of Nile tilapia (Oreochromis niloticus), a tropical fish of significant economic importance, under cold stress.
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