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Background: Traumatic brain injury (TBI) is considered a major cause of death globally, resulting from trauma. Decompressive craniectomy (DC) may improve functional outcomes in patients with TBI and its associated complications. This study was designed to determine safety and efficacy of DC in improving clinical outcomes in TBI patients compared to standard therapy.

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With the increasing detection rate of Internet addiction in college students, the correlation between Internet addiction and emotional problems is further strengthened. Therefore, it is crucial to actively investigate the emotional mechanisms underlying college students' internet addiction to foster their healthy development. This study establishes a moderated mediation model based on the relationships among experiential avoidance, internet addiction, anxiety, and difficulty describing feelings to explore the link between experiential avoidance and internet addiction, the mediating role of anxiety, and the moderating effect of difficulty describing feelings.

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Background: Sodium-glucose cotransporter-2 inhibitors (SGLT2is) are known for their cardiovascular benefits, but their impact on serum uric acid levels is not well understood. This study evaluates the hypouricemic effects of SGLT2is and their potential cardiovascular implications.

Methods: A network meta-analysis was performed, including 56 studies (16,788 participants) contributing data to the meta-analysis.

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Manganese-Catalyzed Electrochemical Amination of Activated Alkenes.

Chem Asian J

January 2025

Visva-Bharati University: Visva-Bharati, Chemistry, Santiniketan Road, 731235, Santiniketan, Bolpur, INDIA.

We have unveiled a new manganese-catalyzed electrochemical amination method to transform activated alkenes into a diverse array of vinyl amines harnessing sodium azide as the aminating reagent. The strategy claims notable versatility by accommodating a broad spectrum of substrates, demonstrating good compatibility with diverse functional groups, as well as delivering a moderate to good range of yields. The successful late-stage functionalization further underscores its practical utility.

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Newly identified SpoVAF/FigP complex: the role in spore germination at moderate high pressure and influencing factors.

Appl Environ Microbiol

January 2025

College of Food Science and Nutritional Engineering, National Engineering Research Center for Fruit and Vegetable Processing, Key Laboratory of Fruit and Vegetable Processing of Ministry of Agriculture and Rural Affairs, Beijing Key Laboratory for Food Non-Thermal Processing, China Agricultural University, Beijing, China.

Unlabelled: The SpoVAF/FigP complex, a newly identified dormant spore ion channel, has been shown to amplify the response of germinant receptors (GRs) to nutrient germinants. However, its contribution to high-pressure-induced germination remains unexplored. In this study, we discovered that the 5AF/FigP complex played an important role in the GR-dependent germination of spores under moderate high pressure (MHP) by facilitating the release of ions, such as potassium (K), a mechanism in parallel with its role in nutrient-induced germination.

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