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Applicability of ToF-SIMS for monitoring compositional changes in bone in a long-term animal model.
J R Soc Interface
September 2013
Institute for Physical Chemistry, Justus-Liebig-University of Giessen, Heinrich-Buff-Ring 58, 35392 Giessen, Germany.
Time-of-flight secondary ion mass spectrometry (ToF-SIMS) is a well-established technique in material sciences but has not yet been widely explored for implementation in life sciences. Here, we demonstrate the applicability and advantages of ToF-SIMS analysis for the study of minerals and biomolecules in osseous tissue. The locally resolved analysis of fragment ions deriving from the sample surface enables imaging and differentiation of bone tissue and facilitates histology on non-stained cross sections.
View Article and Find Full Text PDF["CLAPSEN", a global approach to the rehabilitation of severe childhood malnutrition in Bolivia].
Sante
September 2000
Faculdad de Medicina, UMSS, CP 3119, Cochabamba, Bolivia.
The "CLAPSEN" approach was developed at the Hospital Materno Infantil German Urquidi in Cochabamba, to provide a global response for the study and treatment of childhood malnutrition. "CLAPSEN" is short for Clinical, Laboratory, Anthropometry, Psychology, Sociology, Nursing (Enfermera in Spanish) and Nutritional care. Most of the malnourished children admitted to Cochabamba Hospital are from poor families, more than three quarters of whom have only recently arrived in the city.
View Article and Find Full Text PDF[Characteristics of multideficiency syndrome in infancy (Kwashiorkor)].
Bol Oficina Sanit Panam
September 1956
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