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Expression of Leukemia Inhibitory Factor (LIF) and p53 on Human Fetal Lung After Chorioamnionitis Suffering.
Cureus
December 2024
Laboratory of Histology-Embryology, Faculty of Health Sciences, Aristotle University of Thessaloniki, Thessaloniki, GRC.
Introduction: Maternal infections such as chorioamnionitis could impact fetal lung development by altering cell proliferation and apoptosis. Chorioamnionitis favors the multiple pleiotropic cytokines production such as LIF (leukemia inhibitory factor) and an inflammation-related protein p53. The cytokine production can lead to lung tissue damage and lung disease development.
View Article and Find Full Text PDFComparison of different fixatives effects in histochemical stainings of peripheral nerve tissue.
Cell Mol Biol (Noisy-le-grand)
January 2025
Harran University Faculty of Veterinary Medicine Department of Anatomy, Sanliurfa, Turkey.
A pathological condition in the peripheral nerve tissue, which provides the connection between the organism and the external environment, negatively affects the standard of living. The nerve tissue histotechnology is of serious importance both for scientific studies and for clinical diagnosis. The fixation, which is one of the leading procedures for histological examination of tissues, aims to preserve tissue morphology.
View Article and Find Full Text PDFHigh-frequency shoot regeneration, assessment of genetic fidelity, and histochemical analysis of forskolin production in Coleus forskohlii Briq.
Protoplasma
November 2024
Department of Agricultural Biotechnology, Bidhan Chandra Krishi Viswavidyalaya, Nadia, Mohanpur, West Bengal, 741252, India.
Article Synopsis
- Forskolin, derived from the roots of Coleus forskohlii, has therapeutic potential and this study aimed to develop a reliable method for regenerating these plants year-round for consistent forskolin production.
- The researchers found that using 1.5 mg/L meta-topolin increased shoot and leaf output significantly, with optimal results achieved through a combination with auxin.
- Results showed high plant survival rates during acclimatization, confirmed genetic fidelity with the mother plant, and a notable increase in forskolin levels in the in vitro roots, suggesting this method could support commercial production and conservation efforts.
Influence of photobiomodulation and radiofrequency on the healing of pressure lesions in mice.
Lasers Med Sci
November 2024
Laboratory of Assessment and Rehabilitation of the Locomotor Apparatus (LARAL), Department of Health Sciences, Universidade Federal de Santa Catarina, Rua Pedro João Pereira, 150, room 111, Mato Alto, Araranguá, Santa Catarin, CEP 88905-120, Brazil.
The objective of this study was to ascertain the impact of photobiomodulation and radiofrequency on the healing of pressure injuries in mice. A total of 70 animals were randomly assigned to seven experimental groups. A pressure injury was induced in the dorsal region of the mice by the application of two magnets.
View Article and Find Full Text PDFAnti-inflammatory oligosaccharide licensed mesenchymal stem cells allow prolonged survival of septic rats via the promotion of glutathione synthesis.
Phytomedicine
December 2024
School of Pharmacy, Jiangsu University, 212013, ZhenJiang, PR China. Electronic address:
Background: Mesenchymal stem cells (MSCs) possess the capability to mitigate multiorgan failure (MOF) and reduce mortality rates in sepsis. However, their survival is significantly limited due to oxidative stress responses triggered by excessive sepsis inflammation. Previous studies have demonstrated that the paracrine effect of MSCs can be enhanced by cytokine stimuli such as IL-1β, TNF-α, and IFN-γ, a process known as inflammatory licensing.
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