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Unlabelled: The most frequent cause of nephritic syndrome in the pediatric population is acute post-infectious glomerulonephritis (PIGN). A rare complication is posterior reversible encephalopathy syndrome (PRES), characterized by subcortical vasogenic cerebral edema associated with variable neurological symptoms. The development of autoimmune hemolytic anemia is an atypical clinical presentation.
View Article and Find Full Text PDFBeyond Classification: A Unique Case of Self-Resolving Cutaneous Mucinosis Associated With Streptococcal Infection in a Child.
Pediatr Dermatol
December 2024
Division of Dermatology, Tel Aviv Sourasky Medical Center, Tel Aviv, Israel.
A 3-year-old boy presented with an unusual combination of indurated skin, sclerotic plaques with lichenification, and yellowish papules. Histopathology revealed diffuse dermal mucin deposits, and laboratory tests showed a positive throat culture for Group A streptococcus and elevated serum anti-streptolysin titers. An 10-day course of oral amoxicillin was associated with near-complete resolution of all dermatological findings within 4 months.
View Article and Find Full Text PDFDetermination of the upper limit of normal for serum anti-streptolysin-O titre in primary school children in Southern Nigeria; A model for other low resource settings.
Int J Cardiol Cardiovasc Risk Prev
June 2024
Department of Child Health, University of Benin Teaching Hospital, PMB 1111, Benin City, Nigeria.
The prevention and treatment of Rheumatic Heart disease is hinged on antibiotic administration in children with Group A (GAS) pharyngitis and Acute Rheumatic Fever (ARF). The Upper Limit of Normal (ULN) for serum Anti-streptolysin O titre (ASOT) has been employed as proof of antecedent GAS pharyngitis to fulfil the Jones' criteria for diagnosis of ARF. This value has not been generated among West African children.
View Article and Find Full Text PDFAcute Rheumatic Fever or Post-streptococcal Reactive Arthritis: Two Different Entities.
Cureus
October 2024
Internal Medicine, Hospital São Teotónio, Viseu, PRT.
Article Synopsis
- A 71-year-old man experienced fever and joint pain after a recent throat infection, showing signs of group A streptococcal (GAS) infection with high antistreptolysin O (ASO) levels.
- The case raised questions about whether he had acute rheumatic fever (ARF) or post-streptococcal reactive arthritis (PSReA), as he displayed symptoms of both conditions.
- The authors highlight the need for careful consideration of ARF in patients with recent streptococcal infections and joint pain to ensure timely treatment and avoid complications.
Acute Post-infectious Glomerulonephritis in Children Admitted to a Tertiary Care Hospital: A Descriptive Cross-sectional Study.
JNMA J Nepal Med Assoc
March 2024
Nepal Medical college and teaching hospital, Jorpati, Kathmandu, Nepal.
Article Synopsis
- Post infectious glomerulonephritis (APIGN) is a leading cause of hospital admissions in children in developing countries, with a study conducted in Nepal examining its prevalence and associated factors.
- The study included 1554 children over three years, revealing a prevalence rate of 4.05% for APIGN, with key clinical findings such as elevated antistreptolysin O titers and low serum C3 levels.
- The findings underscore the continuing health risk posed by APIGN in children and the importance of surveillance and management strategies in addressing this issue in areas like Nepal.
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