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Early Positive Report of Viloxazine for a Child with Hyperkinetic Autism.
Psychopharmacol Bull
January 2025
Alamiri, MD, ABPN, ScD, Al-Manara CAP Centre, Kuwait Centre for Mental Health (KCMH), Shuwaikh, State of Kuwait.
Herein, authors report on an ASD child with comorbid ADHD, ID, metabolic syndrome and nocturnal enuresis that failed multiple trials of psychotropic agents for behavioural dyscontrol. Viloxazine adjuventia brought about remarkable improvement spanning different domains. Purported pharmacodynamic mechanisms are briefly discussed.
View Article and Find Full Text PDFPrevalence of psychiatric comorbidities in females with classic congenital adrenal hyperplasia.
J Clin Endocrinol Metab
December 2024
Susan B. Meister Child Health and Evaluation Research Center, University of Michigan Medical School, Ann Arbor, MI, USA.
Article Synopsis
- The study examines the mental health challenges faced by patients with classic congenital adrenal hyperplasia (CAH) compared to matched groups from the general population and women with type-1 diabetes mellitus (T1DM).
- Researchers found that CAH patients showed higher rates of psychiatric issues, like depression and anxiety, than those in the general population, but similar rates to those with T1DM.
- The findings suggest that while living with CAH contributes to mental health problems, it may intersect with issues faced by individuals managing any chronic medical condition, highlighting the need for further research on their long-term mental health outcomes.
Effect of desmopressin on water and solute circadian rhythms in treatment-naïve children with monosymptomatic enuresis and nocturnal polyuria.
Pediatr Nephrol
November 2024
Department of Internal Medicine and Pediatrics, Ghent University, Ghent, Belgium.
Background: Enuresis has a complex pathophysiology involving nocturnal polyuria, reduced bladder capacity at nighttime, and impaired arousability. Desmopressin has long been used as a treatment. However, approximately 30% of children do not fully respond to it, suggesting the involvement of other factors.
View Article and Find Full Text PDFFunctional connectivity density of brain in children with primary nocturnal enuresis: results from a resting-state fMRI study.
Eur Child Adolesc Psychiatry
October 2024
Department of Radiology, Tianjin Key Lab of Functional Imaging & Tianjin Institute of Radiology, Tianjin Medical University General Hospital, Tianjin, 300052, China.
Article Synopsis
- Primary nocturnal enuresis (PNE) is a condition where children involuntarily urinate during sleep after age five, leading to emotional and social challenges for them and their families.
- Recent research indicates that delayed brain development may be a significant factor contributing to PNE, with previous studies highlighting changes in specific brain regions but not overall brain connectivity.
- This study assessed brain connectivity across the entire brain, finding reduced functional connectivity in certain regions associated with hyperactivity and impulsivity in children with PNE, thus offering new insights into its underlying neural mechanisms.
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