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Background: The 15° left tilt position during caesarean delivery has been recommended by guidelines for many years, but recent studies have questioned the clinical benefit of left tilt position. We hypothesize that using a higher starting dose of metaraminol in the supine position will result in a non-inferior umbilical arterial pH, compared to the 15° left tilt position.

Methods: Healthy women undergoing elective caesarean delivery were randomized to the supine position (n = 62) or 15° left tilt position (n = 62) after spinal anaesthesia (0.

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  • Acute kidney injury (AKI) often occurs in patients with vasodilatory shock and is linked to higher mortality rates, longer hospital stays, and potential chronic kidney disease.
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Background: Peripherally administered vasopressor infusions are used to support critically ill patients. The Intensive Care Society recently published guidelines supporting their use. Preliminary evidence suggests variability in peripheral vasopressor infusion use.

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Department of Clinical Pharmacology, Chengdu Fifth People's Hospital, Chengdu, China.

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  • Zoledronic acid, a common treatment for osteoporosis, was implicated in a rare case of severe sepsis in a 58-year-old woman with underlying health conditions.
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Metabolic Patterns of Fluconazole Resistant and Susceptible Clade V and I.

J Fungi (Basel)

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Department of Molecular Microbiology & Immunology, South Texas Center for Emerging Infectious Diseases, The University of Texas at San Antonio, San Antonio, TX 78249, USA.

, an emerging non- multidrug-resistant yeast, has become a significant cause of invasive candidiasis in healthcare settings. So far, data on the metabolites of in different clades are minimal, and no studies have focused on clade V metabolites. Therefore, Gas chromatography-mass spectrometry (GC-MS) was used for the metabolomic profiling of clade I compared with fluconazole-resistant and susceptible in clade V strains.

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