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Nutrition therapy for critically ill patients - Five key problems.

Clin Nutr

January 2025

Department of Intensive Care Medicine, University Medical Centre Hamburg-Eppendorf, Germany. Electronic address:

Background & Aims: A pragmatic trial and its secondary analyses have demonstrated that nutritional care not only reduces complications but also significantly improves survival in medical patients at risk of malnutrition. In contrast, for critically ill patients comparable evidence is scarce. Consequently, many propositions for refining the research agenda and study design in the field of critical care nutrition have already been made.

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Expanded Uses of the Dorsal Nasal Flap: Redefining the Nasal Reconstruction Algorithm.

Plast Reconstr Surg Glob Open

January 2025

From the Department of Plastic and Reconstructive Surgery, Lahey Hospital and Medical Center, Burlington, MA.

Background: Defects of the nose present complex reconstructive challenges to the plastic surgeon. We present our experience with using the dorsal nasal flap (DNF) to provide a durable reconstruction even in sizable defects that would otherwise be considered necessitating a paramedian forehead flap.

Methods: We conducted a retrospective chart review of patients who underwent reconstruction by DNF following resection of skin cancers on the nose.

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Ethical and security challenges in AI for forensic genetics: From bias to adversarial attacks.

Forensic Sci Int Genet

January 2025

Computer Science Department, University of Buenos Aires, Faculty of Exact and Natural Sciences, Buenos Aires, Argentina.

Forensic scientists play a crucial role in assigning probabilities to evidence based on competing hypotheses, which is fundamental in legal contexts where propositions are presented usually by prosecution and defense. The likelihood ratio (LR) is a well-established metric for quantifying the statistical weight of the evidence, facilitating the comparison of probabilities under these hypotheses. Developing accurate LR models is inherently complex, as it relies on cumulative scientific knowledge.

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Background: Health authorities worldwide have invested in digital technologies to establish robust information exchange systems for improving the safety and efficiency of medication management. Nevertheless, inaccurate medication lists and information gaps are common, particularly during care transitions, leading to avoidable harm, inefficiencies, and increased costs. Besides fragmented health care processes, the inconsistent incorporation of patient-driven changes contributes to these problems.

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Background: Increased taxation on alcohol and tobacco is among the cost-effective measures used to deal with the burden of noncommunicable diseases (NCDs) globally. Despite adopting such efforts, the impacts of taxation on alcohol and tobacco are yet to be fully understood.

Objective: The study's objective is to find empirical evidence regarding changes in the NCD mortality rate associated with changes in the tax rates of tobacco and alcohol.

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