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Elucidating the molecular and immune interplay between head and neck squamous cell carcinoma and diffuse large B-cell lymphoma through bioinformatics and machine learning.
Transl Cancer Res
November 2024
School of Life Sciences, Jiangsu University, Zhenjiang, China.
Background: Head and neck squamous cell carcinoma (HNSCC) contributes significantly to global health challenges, presenting primarily in the oral cavity, pharynx, nasopharynx, and larynx. HNSCC has a high propensity for lymphatic metastasis. Diffuse large B-cell lymphoma (DLBCL), the most common subtype of non-Hodgkin lymphoma, exhibits significant heterogeneity and aggressive behavior, leading to high mortality rates.
View Article and Find Full Text PDFPrimary Laryngeal Lymphoma: A Case Report of a Rare Entity.
Cureus
October 2024
Otorhinolaryngology, Saveetha institute of medical and technical sciences, Chennai, IND.
Article Synopsis
- * A case study of a 53-year-old male with symptoms like weight loss, hoarseness, and dysphagia led to the diagnosis of diffuse large B-cell lymphoma (DLBCL) through a biopsy, following imaging that revealed a significant lesion in the larynx.
- * The patient successfully underwent eight cycles of CHOP chemotherapy, resulting in complete remission with no recurrence in two years, highlighting the need for early detection and treatment due to symptom similarities with other laryngeal issues.
Laryngeal non-Hodgkin lymphoma: Report of four cases and review of the literature.
Open Life Sci
September 2024
Department of Otolaryngology Head and Neck Surgery, The Affiliated Hospital of Southwest Medical University, No. 25 Taiping Street, Jiangyang District, Luzhou, Sichuan, 646000, China.
Article Synopsis
- * The first three patients had different types of laryngeal NHL and received various treatments, including surgery, radiotherapy, and chemotherapy.
- * The authors conclude that further research and more case reports are necessary to better understand and treat this condition.
[Primary laryngeal lymphoma: a case report].
Pan Afr Med J
July 2024
Université Sidi Mohamed Ben Abdellah, Faculté de Médecine et de Pharmacie de Fès, Centre Hospitalier Universitaire HASSAN II, Fès, Service Oto-Rhino-Laryngologie et Chirurgie Cervico-Faciale, Fès, Maroc.
Article Synopsis
- Primary laryngeal lymphoma is a rare type of cancer, making up less than 1% of laryngeal cancers and its treatment varies based on the disease's stage and severity.
- A case study describes a 64-year-old woman with dysphagia (difficulty swallowing) and a feeling of something stuck in her throat, which led to the discovery of a tumor diagnosed as diffuse large B-cell lymphoma after laryngoscopy and biopsies.
- The patient underwent chemotherapy followed by radiotherapy and showed significant improvement after 2 years, highlighting the need for tailored diagnostic and treatment strategies due to the rarity and diverse symptoms of this cancer.
Extranodal marginal zone lymphoma of the larynx: A case report and scoping review.
Head Neck
December 2024
Northwell Health, New Hyde Park, New York, USA.
Background: This scoping review aims to review cases of extranodal marginal zone lymphoma (MZL) of the larynx to establish best management practices for this rare clinical entity.
Methods: In this paper, we report a case of laryngeal MZL, in accordance with CARE guidelines. We then performed a scoping review according to PRISMA-ScR criteria of published cases of MZL involving the larynx.
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