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Male ejaculation acutely suppresses sexual motivation in male mice. In contrast, relatively little is known about how male ejaculation affects sexual motivation and sexual behavior in female mice. How the brain responds to the completion of mating is also unclear.

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Background: The fertility of roosters significantly impacts the economic outcome of the poultry industry. However, it is common for some roosters to fail to produce semen during production, and the underlying reasons remain largely unclear.

Results: To investigate a solution to this problem, induced molting (IM) was performed on no-semen (NS) roosters.

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Preclinical development of a novel injectable hydrogel for vas-occlusion.

Contraception

February 2025

Contraline, Inc, Charlottesville, VA, United States. Electronic address:

Objectives: The objective of this work is to outline the preclinical development of ADAM, an injectable, two-component polyethylene glycol hydrogel designed for long-lasting and nonpermanent vas-occlusive contraception.

Study Design: A newly developed hydrogel was comprehensively characterized to evaluate its potential as a male contraceptive device. The material was optimized for porosity to ensure sperm occlusion, rheological properties, injectability, and mechanical durability within the dynamic vessel.

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