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Pilomatrix carcinoma unveiled: a systematic review of clinical characteristics, pathogenesis, diagnostic puzzles, and management strategies.
Arch Dermatol Res
January 2025
Premier Dermatology, Ashburn, VA, USA.
Pilomatrix carcinoma (PC) is a rare malignant adnexal tumor originating from follicular matrix cells primarily impacting Caucasian males. This review provides a comprehensive analysis of scientific literature on PC through an exploration of 206 cases reported between 1980 and 2024. We discuss the epidemiology, clinical presentation, histopathology, and diagnostic challenges of PC, and explore various treatment methods for this rare malignancy as well as their associated outcomes.
View Article and Find Full Text PDFCervical Neuroendocrine Carcinoma Presenting as Isolated Large Ovarian Metastasis: A Case Report.
Am J Case Rep
January 2025
Department of Obstetrics and Gynecology, Faculty of Medicine, Dr Soetomo General Hospital, Universitas Airlangga, Surabaya, East Java, Indonesia.
BACKGROUND Neuroendocrine carcinoma (NEC) of the cervix is rare and has high mortality and recurrence rates. The clinical symptoms of cervical NEC, such as abnormal vaginal bleeding and discharge, are similar to those of other cervical cancers. Here, we describe a case involving a 42-year-old woman with cervical NEC accompanied by an isolated large ovarian metastasis.
View Article and Find Full Text PDFImaging Characteristics of Primary Mucinous Cystadenocarcinoma of the Breast: A Case Report and Literature Review.
Curr Med Imaging
January 2025
Department of Pathology, Affiliated Jinhua Hospital Zhejiang University School of Medicine, Jinhua, Zhejiang, 32100, P. R. China.
Introduction: Mucinous Cystadenocarcinoma (MCA) of the breast remains a relatively rare condition, and to date, there is no systematic summary of its imaging manifestations. Therefore, this report presents a detailed account of the diagnosis and treatment of mucinous cystadenocarcinoma in a 40-year-old woman, with a particular focus on imaging findings. Additionally, we conducted a comprehensive literature review on this disease and summarized its key imaging features.
View Article and Find Full Text PDFSurgical treatment of pilomatrix carcinoma: a systematic review.
Int J Dermatol
December 2024
Division of Dermatology, Baylor University Medical Center, Dallas, Texas, USA.
Article Synopsis
- Pilomatrix carcinoma (PMC) is a rare and aggressive hair follicle tumor with high recurrence and metastasis risks, often stemming from benign pilomatricoma or arising independently.
- A study analyzed various surgical treatments for PMC by reviewing 257 articles from major databases, ultimately including 50 relevant studies, highlighting the effectiveness of different surgical methods.
- The findings revealed that Mohs micrographic surgery (MMS) had no recurrences in 17 treated cases, while surgical excision resulted in a 34.5% recurrence rate, suggesting that MMS is a superior option to minimize recurrence and preserve tissue.
Atypical and giant proliferating pilomatrixoma of the eyelid: a clinicopathological report.
BMC Ophthalmol
November 2024
Department of Oculo-Facial Plastic and Reconstructive Surgery, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Background: Pilomatrixoma is an uncommon benign skin neoplasm originating from the hair follicle. Here, we report a rare case of giant and atypical proliferating pilomatrixoma affecting the eyelid.
Case Presentation: A 47-year-old male presented with a solitary, giant mass on his left upper eyelid, which had recently shown progressive enlargement.
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