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Low-grade mucinous neoplasm originating from intestinal duplication: a case report and review of the literature.
World J Surg Oncol
January 2025
Cancer Center, Department of Pathology, Zhejiang Provincial People's Hospital, Affiliated People's Hospital, Hangzhou Medical College, 158 Shangtang Road, Hangzhou, Zhejiang, 310014, China.
Background: Low-grade mucinous neoplasms typically originate from the appendix and are characterized by a lining of low-grade mucus-secreting columnar epithelial cells and smooth muscle. However, atypical origins can occur, as demonstrated in this case report.
Case Presentation: We present a case involving a 33-year-old male who, upon physical examination, was found to have an abdominal mass.
Analysis of survival and prognostic factors in appendix adenocarcinoma and mucinous carcinoma.
Updates Surg
January 2025
Suleyman Demirel Univercity, Isparta, Turkey.
This study aimed to compare mucinous carcinoma and adenocarcinoma of the appendix in terms of survival and investigate the risk factors influencing survival. The data for this study were retrieved from the SEER database (SEER Research Plus 17 registries). Patients diagnosed with appendix cancer between 2004 and 2019 were included.
View Article and Find Full Text PDFCell of origin and expression profiles of pseudomyxoma peritonei derived from the appendix.
Pathol Res Pract
December 2024
Division of Clinical Genome Research, Institute of Medical Science, The University of Tokyo, Tokyo, Japan. Electronic address:
Article Synopsis
- Pseudomyxoma peritonei (PMP) is a rare condition linked to mucin-producing tumors, usually starting in the appendix, leading to mucin buildup in the abdomen.
- Researchers conducted RNA-seq analysis on ten PMP cases and their healthy tissue to reveal 32 differently expressed genes, indicating that PMP tumors arise from goblet cells.
- The study found significant associations between PMP tumors and important biological processes like epithelial-mesenchymal transition, angiogenesis, and inflammation, with further analysis highlighting distinct gene expressions in different PMP types, suggesting more aggressive traits in peritoneal mucinous adenocarcinomas (PMCA).
Should an Interval Appendicectomy Be Performed by a Minimally Invasive Gynaecologist?
Int J Womens Health
December 2024
Sydney Women's Endosurgery Centre (SWEC), St George Hospital, Sydney, NSW, Australia.
Objective: We aimed to explore the abnormal pathology findings in appendix specimens removed based on intraoperative abnormal appearance during elective surgery for benign gynaecological conditions by a minimally invasive gynaecologist, as well as the associated complication rate.
Materials And Methods: This retrospective cohort study was conducted in a tertiary referral surgical centre for benign gynaecological conditions between the years 2004-2023. It included patients who underwent appendicectomy by a trained minimally invasive gynaecologist based on observations during surgery for benign gynaecological conditions.
Low-grade appendiceal mucinous neoplasm: A case report.
Medicine (Baltimore)
December 2024
Department of General Surgery, Nujiang Prefecture People's Hospital, Nujiang, Yunnan, China.
Rationale: Low-grade appendiceal mucinous neoplasm (LAMN) is a clinically rare tumor that predominantly occurs in females and presents with nonspecific symptoms, often resulting in misdiagnosis. While postoperative pathology remains the gold standard for diagnosis, accurate preoperative identification through various diagnostic methods is essential for effective treatment planning. To raise awareness of this condition, we present a case of a middle-aged male diagnosed with LAMN.
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