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Alcohol use and HIV suppression after completion of financial incentives for alcohol abstinence and isoniazid adherence: a randomized controlled trial.
EClinicalMedicine
February 2025
Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Background: In a recent randomized trial, six months of financial incentives contingent for recent alcohol abstinence led to lower levels of hazardous drinking, while incentives for recent isoniazid (INH) ingestion had no impact on INH adherence, during TB preventive therapy among persons with HIV (PWH). Whether the short-term incentives influence long-term alcohol use and HIV viral suppression post-intervention is unknown.
Methods: We analyzed twelve-month HIV viral suppression and alcohol use in the Drinkers' Intervention to Prevent Tuberculosis study, a randomized controlled trial among PWH with latent TB and unhealthy alcohol use in south-western Uganda.
The relationship between psychological abuse, athlete satisfaction, eating disorder and self-harm indicators in elite athletes.
Front Sports Act Living
January 2025
Faculty of Kinesiology and Physical Education, University of Toronto, Toronto, ON, Canada.
Introduction: Psychological abuse continues to be the most frequently reported type of maltreatment among athletes leading to negative mental health such as low mood and self-esteem, increased anxiety, self-harm, and eating disorders. Preliminary evidence suggests athlete satisfaction can influence the perceived outcomes associated with psychological abuse. Despite its negative impacts on athletes, psychological abuse continues to be justified as a tool to enhance athletic performance.
View Article and Find Full Text PDFIntermittent Sinus Pause/Asystole in the Setting of Anticholinergic Overdose.
Cureus
January 2025
Emergency Medicine, Western Michigan University Homer Stryker M.D. School of Medicine, Kalamazoo, USA.
Anticholinergic toxicity typically presents with symptoms of cutaneous vasodilation, delirium, mydriasis, urinary retention, hyperthermia, anhidrosis, and tachycardia. This case report presents a 68-year-old female patient who exhibited some of these signs and symptoms after ingesting an unknown quantity of dicyclomine. However, she displayed one notable exception to the classic toxidrome.
View Article and Find Full Text PDFPerception of without infection induces in .
MicroPubl Biol
January 2025
Molecular and Integrative Physiology Department, University of Michigan-Ann Arbor, Ann Arbor, Michigan, United States.
pathogenic susceptibility is influenced by the worm's detection of its environment and its capacity to resist and resolve damage following infection. Here, we use a model where worms can sense, but not ingest, the pathogen (EF) We identify that perception of EF without infection induces the stress-response gene further identify that neural and intestinal signaling genes are necessary for induction without active infection. Finally, we show that overexpression is sufficient to extend lifespan with EF exposure, while KO is not detrimental, suggesting that additional expression benefits worms in this condition.
View Article and Find Full Text PDFAvoidant/Restrictive Food Intake Disorder in a Pediatric Obese Patient.
Cureus
December 2024
Pediatrics, Dr. Efrain Flores Pediatrics, Bolingbrook, USA.
Avoidant/restrictive food intake disorder (ARFID) can present with limited food variety, intake, or aversions. The symptoms can manifest at any age and typically appear in the first few years of life. The prevalence of ARFID varies widely among clinical and non-clinical populations, and its diagnosis requires trained health professionals to ensure early detection and prevention of poor outcomes.
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