Effect of the medium with high partial pressure of helium and nitrogen on the content of di- and triphosphinositides in the rat brain great hemispheres. The stay of the rats in helium-oxygen mixture under the pressure of 40 kg/cm2 for 1 h is accompanied by the true decrease in the content of the both components of polyphosphoinositides whose value does not depend on the decompression conditions. Nitrogen-oxygen mixture under the pressure of 15 and 25 kgf/cm2 also evokes a decrease of the content of di- and triphosphoinositides. The character of reduction of the content of the both components for 4 h after the stay of the rats under the pressure of 25 kgf/cm2 depends on the decompression conditions.

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