Effect of the medium with high partial pressure of helium and nitrogen on the content of di- and triphosphinositides in the rat brain great hemispheres. The stay of the rats in helium-oxygen mixture under the pressure of 40 kg/cm2 for 1 h is accompanied by the true decrease in the content of the both components of polyphosphoinositides whose value does not depend on the decompression conditions. Nitrogen-oxygen mixture under the pressure of 15 and 25 kgf/cm2 also evokes a decrease of the content of di- and triphosphoinositides. The character of reduction of the content of the both components for 4 h after the stay of the rats under the pressure of 25 kgf/cm2 depends on the decompression conditions.
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J Occup Health
January 2025
Department of Occupational and Environmental Health, Faculty of Pharmaceutical Sciences, Tokyo University of Science, Noda, Japan.
Bromopropane was introduced commercially as an alternative to ozone-depleting and global warming solvents. The identification of 1-bromopropane neurotoxicity in animal experiments was followed by reports of human cases of 1-bromopropane toxicity. In humans, the most common clinical features of 1-bromopropane neurotoxicity are decreased sensation, weakness in extremities, and walking difficulties.
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Programa de Pós-Graduação em Ciências Biológicas: Bioquímica, Instituto de Ciências Básicas da Saúde, Universidade Federal do Rio Grande do Sul, Porto Alegre, RS, Brazil.
Resveratrol, a natural polyphenol, has shown promising neuroprotective effects in several in vivo and in vitro experimental models. However, the mechanisms by which resveratrol mediates these effects are not fully understood. Glutamate is the major excitatory neurotransmitter in the brain; however, excessive extracellular glutamate levels can affect neural activity in several neurological diseases.
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Department of Biochemistry and Molecular Biology, Faculty of Veterinary Medicine, Shahid Chamran University of Ahvaz, Ahvaz, Iran.
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Neurosciences Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
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View Article and Find Full Text PDFJ Neuropathol Exp Neurol
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Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, NY, United States.
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