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Correlation of ACE gene polymorphisms and platelet parameters with morning peak blood pressure in hypertensive patients.
Am J Transl Res
December 2024
Department of Cardiology, Wujin Hospital Affiliated with Jiangsu University Changzhou 213004, Jiangsu, China.
Objective: To analyze the relationship between platelet parameters, morning peak blood pressure (MPBP) in hypertensive patients, and angiotensin-converting enzyme (ACE) gene polymorphisms.
Methods: This study included 245 primary hypertensive patients treated between February 2019 and February 2022, who were divided into two groups based on MPBP status: 144 patients with MPBP and 101 without MPBP. Baseline data and early morning fasting blood samples from the antecubital vein were collected.
Left atrial reservoir strain as a predictor of cardiac dysfunction in a murine model of pressure overload.
Acta Physiol (Oxf)
February 2025
PhyMedExp, IPAM/Biocampus, University of Montpellier, INSERM, CNRS., Montpellier, France.
Aim: Left atrial (LA) strain is emerging as a valuable metric for evaluating cardiac function, particularly under pathological conditions such as pressure overload. This preclinical study investigates the predictive utility of LA strain on cardiac function in a murine model subjected to pressure overload, mimicking pathologies such as hypertension and aortic stenosis.
Methods: High-resolution ultrasound was performed in a cohort of mice (n = 16) to evaluate left atrial and left ventricular function at baseline and 2 and 4 weeks after transverse aortic constriction (TAC).
Pre-Lithiated Silicon-Based Composite Anode for High-Performance All-Solid-State Batteries.
Small
January 2025
College of Energy, Xiamen University, Xiamen, Fujian, 361102, China.
Silicon is widely recognized as a promising anode material for all-solid-state batteries (ASSBs) due to exceptional specific capacity, abundant availability, and environmental sustainability. However, the considerable volume expansion and particle fragmentation of Si during cycling lead to significant performance degradation, limiting its practical application. Herein, the development of a pre-lithiated Si-based composite anode (c-LiSi) is presented, designed to address the key challenges faced by Si-based anodes, namely severe volume changes and low electrochemical stability.
View Article and Find Full Text PDFOptimizing the hyperbaric chamber pressurization profile during standard hyperbaric oxygen therapy.
Undersea Hyperb Med
January 2025
King Hamad American Mission Hospital, A'ali, Kingdom of Bahrain.
Middle ear barotrauma (MEBT) is the most common complication in providing hyperbaric oxygen therapy (HBO). This study explored the impact of altering the shape of the time-pressure curve with the aim of reducing the occurrence of MEBT and optimizing the HBO experience during the pressurization process. Four distinct mathematically derived protocols-Constant Pressure Difference (CPD), Constant Volume Difference (CVD), Constant Ratio (CR), and Inverted Constant Ratio (ICR)-were investigated using computer simulations on a simple ear model.
View Article and Find Full Text PDFNavigating the Waves of Critical Care Echocardiography: Unveiling its Role, Advantages, and Pitfalls in the Cardiac Intensive Care Unit.
Curr Cardiol Rep
January 2025
Department of Cardiovascular Disease, Mayo Clinic, Rochester, MN, USA.
Purpose Of Review: Critical Care Echocardiography (CCE) is now established as an important tool in the intensive care unit (ICU). This paper aims to examine the expanding role of cardiovascular ultrasound in the ICU, focusing on its applications, benefits, and challenges, while highlighting recent advancements shaping the future of critical care echocardiography.
Recent Findings: Non-invasive echocardiographic measurement of hemodynamic parameters including stroke volume, cardiac output, left ventricular filling pressures, and pulmonary pressures have been well-validated against invasive measurements.
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