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Adding 6 months of androgen deprivation therapy to postoperative radiotherapy for prostate cancer: a comparison of short-course versus no androgen deprivation therapy in the RADICALS-HD randomised controlled trial.
Lancet
June 2024
MRC Clinical Trials Unit at UCL, Institute of Clinical Trials and Methodology, University College London, London, UK. Electronic address:
Article Synopsis
- A clinical trial called RADICALS-HD studied the effects of adding short-course androgen deprivation therapy (ADT) to postoperative radiotherapy in patients with localized prostate cancer after surgery.
- It involved 1480 patients, examining how ADT impacts metastasis-free survival compared to radiotherapy alone, and measured outcomes like distant metastasis and overall survival.
- The trial aimed to see if combining ADT with radiotherapy could improve the 10-year metastasis-free survival rate, potentially increasing it from 80% to 86%.
Low-dose oral minoxidil improves hair length and global hair density in short anagen syndrome.
J Am Acad Dermatol
August 2024
Sinclair Dermatology, East Melbourne, VIC, Australia; Faculty of Medicine, University of Melbourne, Melbourne, VIC, Australia.
Assessment of Interaural Attenuation in Infants and Young Children Using Bone-Conducted Auditory Brainstem Response.
Ear Hear
June 2024
Department of Communication Disorders, Ariel University, Ariel, Israel.
Objectives: In hearing assessment, the term interaural attenuation (IAA) is used to quantify the reduction in test signal intensity as it crosses from the side of the test ear to the nontest ear. In the auditory brainstem response (ABR) testing of infants and young children, the size of the IAA of bone-conducted (BC) stimuli is essential for the appropriate use of masking, which is needed for the accurate measurement of BC ABR thresholds. This study aimed to assess the IAA for BC ABR testing using 0.
View Article and Find Full Text PDFSwitching between tofacitinib and baricitinib in alopecia areata: A review of clinical response.
J Am Acad Dermatol
December 2023
Sinclair Dermatology, East Melbourne, Victoria, Australia; The University of Melbourne, Melbourne, Victoria, Australia.
Advancing Research in Health Professions Education Through an Innovative Accelerator Panel.
J Contin Educ Health Prof
December 2022
Dr. Kawczak: Co-Director, Center for Continuing Education, Assistant Professor of Medicine, Cleveland Clinic, Cleveland, OH. Dr. Stoller: Chairman, Education Institute, Professor of Medicine, Samson Global Leadership Academy Endowed Chair, Cleveland Clinic, Cleveland, OH.
Introduction: Research and scholarship are critical to advance the effective design, implementation, and evaluation of health professions education activities as well as to study outcomes and disseminate observations to the community. Yet, many educators are neither involved in nor equipped to conduct quality education research. This gap underscores the continuing education need to guide and train health professions educators to rigorously investigate, prepare, and report their educational research.
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