Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1055/s-2007-1007399 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Impact of population screening for Lynch syndrome insights from the All of Us data.
Nat Commun
January 2025
Division of Digestive and Liver Diseases, Herbert Irving Comprehensive Cancer Center, Vagelos College of Physicians and Surgeons, Columbia University Irving Medical Center, New York, NY, USA.
Lynch Syndrome (LS) is a common genetic cancer condition that allows for personalized cancer prevention and early cancer detection in identified gene carriers. We used data from the All of Us (AOU) Research Initiative to assess the prevalence of LS in the general U.S.
View Article and Find Full Text PDF[Technical standards for performing radiofrequency catheter ablation for atrial fibrillation: a series of consortium standards].
Zhonghua Nei Ke Za Zhi
January 2025
Atrial fibrillation (AF) has emerged as a major global cardiovascular disease in the 21st century. In China, there are greater than 12 million patients with AF, and its incidence continues to rise. AF affects patients' quality of life and significantly increases the risks of mortality, stroke, heart failure, cognitive impairment, and dementia.
View Article and Find Full Text PDFConstruction and biological function of gene knockout strain.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
August 2024
Department of Parasitology, School of Basic Medical Sciences, Central South University, Changsha 410013.
Objectives: Toxoplasmosis is a zoonotic parasitic disease caused by (), which can lead to complications such as encephalitis and ocular toxoplasmosis. The disease becomes more severe when the host's immune system is compromised. Rhoptry proteins are major virulence factors that enable to invade host cells.
View Article and Find Full Text PDFLow-avidity T cells drive endogenous tumor immunity in mice and humans.
Nat Immunol
January 2025
Department of Immunology and Neag Comprehensive Cancer Center, University of Connecticut School of Medicine, Farmington, CT, USA.
T cells recognize neoepitope peptide-major histocompatibility complex class I on cancer cells. The strength (or avidity) of the T cell receptor-peptide-major histocompatibility complex class I interaction is a critical variable in immune control of cancers. Here, we analyze neoepitope-specific CD8 cells of distinct avidities and show that low-avidity T cells are the sole mediators of cancer control in mice and are solely responsive to checkpoint blockade in mice and humans.
View Article and Find Full Text PDFA dataset of structural breaks in greenhouse gas emissions for climate policy evaluation.
Sci Data
January 2025
Department of Economics, Vienna University of Economics and Business (WU), Vienna, Austria.
The quantitative assessment of policies aimed at climate change mitigation requires rigorously identifying abnormal changes in greenhouse gas emissions. We present a new dataset of robust level changes in greenhouse gas emissions that cannot be explained by aggregate socioeconomic fluctuations. Modern methods of structural break identification based on two-way fixed effects models are employed to estimate the size of significant level changes in emissions.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!