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Graves' disease thyroid dermopathy: a case report.
J Med Case Rep
April 2024
Department of Pediatrics, King Faisal Specialist Hospital and Research Centre, Al Takhassousi & 12713, 11211, Riyadh, Saudi Arabia.
Article Synopsis
- Graves' disease is an autoimmune disorder leading to thyroid gland enlargement and overactivity, with various symptoms affecting multiple organ systems, including thyroid-related skin conditions.
- The case presented involves an 11-year-old boy from Saudi Arabia with symptoms like goiter and bulging eyes, alongside unusual swelling and nodules on his body that resembled a lymphatic issue.
- Treatment options including steroid injections and total thyroid removal improved the patient's condition, highlighting the rare manifestations of thyroid dermopathy in this case.
Article Synopsis
- Pretibial myxedema is a rare skin condition associated with Graves' disease that can be effectively treated with topical glucocorticoids over the long term.!* -
- A case involving a 70-year-old male with hyperthyroidism but no prior Graves' diagnosis showed that the combination of topical corticosteroids and antithyroid medications resulted in significant improvement of the skin lesions.!* -
- This case highlights the need to recognize pretibial myxedema even in unusual cases of Graves' disease and the importance of starting treatment quickly for better outcomes.!*
Life-Threatening Endocrinological Immune-Related Adverse Events of Immune Checkpoint Inhibitor Therapy.
Cancers (Basel)
December 2023
Department and Clinic of Internal Medicine, Angiology, and Physical Medicine, Faculty of Medical Sciences in Zabrze, Medical University of Silesia, Batorego 15 St., 41-902 Bytom, Poland.
Malignant neoplasms are currently one of the leading causes of morbidity and mortality worldwide, posing a major public health challenge. However, recent advances in research in cancer biology and immunity have led to the development of immunotherapy, which is now used on an everyday basis in cancer treatment in addition to surgical treatment, classical cytostatics, and radiotherapy. The efficacy of immunotherapy has promoted the great popularity of this treatment among patients, as well as significant research interest.
View Article and Find Full Text PDFThe realistic positioning of UVA1 phototherapy after 25 years of clinical experience and the availability of new biologics and small molecules: a retrospective clinical study.
Front Med (Lausanne)
November 2023
Department of Dermatology, University of Brescia, Brescia, Italy.
Article Synopsis
- Ultraviolet (UVA) A1 phototherapy has been an effective treatment for various skin conditions since the 1990s, yet its application remains limited to a few dermatology centers even after 30 years.
- A study at a single center reviewed 740 patients treated from 1998 to 2022, assessing treatment outcomes and side effects, revealing significant improvements in several conditions, including morphea and skin sarcoidosis.
- Despite showing good efficacy, the usage of UVA1 phototherapy has decreased over the years due to multiple factors, including possible changes in clinical practices and alternatives available.
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