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In mice, variability in adult bone size and density has been observed among common inbred strains. Also, in the group of genes regulating circadian rhythmicity in mice, so called clock genes, changes in body size and skeletal parameters have been noted in knockout mice. Here, we studied the size and density of prominent bones of the axial and appendicular skeleton of clock gene Period-1-deficient (Per1) mice by means of microcomputed tomography.

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High-Pressure Processing Influences Antibiotic Resistance Gene Transfer in Isolated from Food and Processing Environments.

Int J Mol Sci

December 2024

Department of Food Microbiology, Meat Technology and Chemistry, Faculty of Food Science, University of Warmia and Mazury, Plac Cieszyński 1, 10-726 Olsztyn, Poland.

The study aimed to assess the high-pressure processing (HPP) impact on antibiotic resistance gene transfer in from food and food processing environments, both in vitro (in microbiological medium) and in situ (in carrot juice), using the membrane filter method. Survival, recovery, and frequency of antibiotic resistance gene transfer analyses were performed by treating samples with HPP at different pressures (200 MPa and 400 MPa). The results showed that the higher pressure (400 MPa) had a significant effect on increasing the transfer frequency of genes such as , encoding fosfomycin resistance, and , , , responsible for tetracycline resistance, both in vitro and in situ.

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As described by early sociological research (Goffman, 1963, Behavior in public places: Notes on the social organization of gatherings), a typical behavioural pattern in public encounters between strangers is so-called Civil Inattention (CI). CI describes a ritual of politely communicating having noticed the other while assuring non-communication intentions. A typical example of showing CI is initially looking at the other person but then quickly averting the gaze.

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Supramarginal Resection of Glioblastoma: A Review.

Neurosurg Clin N Am

January 2025

Department of Neurosurgery, Baylor College of Medicine, 7200 Cambridge Street, Houston, TX 77030, USA. Electronic address:

This article discusses the evidence supporting the resection of glioblastoma beyond the borders of contrast-enhancing tumor. While several techniques for this have been described, including a so-called FLAIRectomy, lobectomy, or via the use of adjuncts such as fluorescence or intraoperative MRI, the optimal extent of additional resection has yet to be established. Many authors have noted a survival benefit with supramarginal resection without significant additional morbidity.

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Background: "Frank autism," recognizable through the first minutes of an interaction, describes a behavioral presentation of a subset of autistic individuals that is closely tied to social communication challenges, and may be linked to so-called "prototypical autism." To date, there is no research on frank autism presentations of autistic adolescents and young adults, nor individuals diagnosed with autism spectrum disorder (ASD) in childhood who do not meet diagnostic criteria during or after adolescence (loss of autism diagnosis, LAD). In addition, there are currently no data on the factors that drive frank autism impressions in these adolescent groups.

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