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First report of the chloroplast and mitochondrial genomes of the Indian pitcher plant, Nepenthes khasiana Hook.f.
BMC Res Notes
January 2025
Bioinformatics Center, North-Eastern Hill University, Shillong, 793022, India.
Objectives: Nepenthes, sometimes known as tropical pitcher plants or monkey cups, is a carnivorous plant genus that contains more than 160 species. Nepenthes khasiana, India's sole representative of the genus, is a rare and endangered dioecious plant endemic to North-east India. Despite the fact that it is a prominent insectivorous plant in the Nepenthaceae family, genomic resources for the species are limited, making genomic breeding and understanding the genetic basis of botanical carnivory difficult.
View Article and Find Full Text PDFAttention deficit/hyperactivity disorder (ADHD) dimensions mediate the relationship between adverse childhood experiences and adult aggression depending on cognitive reappraisal.
Sci Rep
January 2025
Institute for Forensic Psychology and Psychiatry, Saarland University, Homburg, Germany.
Associations between adverse childhood experiences (ACEs) and aggressive behavior have often been demonstrated, but the mechanisms underneath these relations are yet unclear. As high levels of ACEs and aggression have been found among individuals with attention deficit/hyperactivity disorder (ADHD), ADHD dimensions might explain this association. Moreover, maladaptive emotion regulation is common in ADHD and was associated with aggressive behavior.
View Article and Find Full Text PDFA new epidemic model of sexually transmittable diseases: a fractional numerical approach.
Sci Rep
January 2025
Department of Mathematics, College of Science Al-Zulfi, Majmaah University, Al-Majmaah 11952, Saudi Arabia.
This study aims at investigating the dynamics of sexually transmitted infectious disease (STID), which is serious health concern. In so doing, the integer order STID model is progressed in to the time-delayed non-integer order STID model by introducing the Caputo fractional derivatives in place of integer order derivatives and including the delay factors in the susceptible and infectious compartments. Moreover, unique existence of the solution for the underlying model is ensured by establishing some benchmark results.
View Article and Find Full Text PDFMitochondrial KMT9 methylates DLAT to control pyruvate dehydrogenase activity and prostate cancer growth.
Nat Commun
January 2025
Klinik für Urologie und Zentrale Klinische Forschung, Klinikum der Universität Freiburg, Freiburg, Germany.
Prostate cancer (PCa) growth depends on de novo lipogenesis controlled by the mitochondrial pyruvate dehydrogenase complex (PDC). In this study, we identify lysine methyltransferase (KMT)9 as a regulator of PDC activity. KMT9 is localized in mitochondria of PCa cells, but not in mitochondria of other tumor cell types.
View Article and Find Full Text PDFSubclinical patterns of cardiac involvement by transthoracic echocardiography in individuals with mild initial COVID-19.
Sci Rep
January 2025
Institute for Experimental and Translational Cardiovascular Imaging, DZHK Centre for Cardiovascular Imaging, Goethe University Frankfurt, Frankfurt am Main, Germany.
The aim of this study was to evaluate the subclinical patterns and evolution of cardiac abnormalities via transthoracic echocardiography (TTE) in patients with mild initial COVID-19 illness. A total of 343 infected individuals (163 males; age 44 (interquartile range, IQR 35-52) years) years) underwent serial TTE assessments at a median of 109 (interquartile range (IQR), 77-177) and 327 (276-379) days after infection. Compared with those of non-COVID-19-infected controls (n = 94, male n = 49), baseline systolic (LVEF, TAPSE) and diastolic function (e', a', E/e') were significantly different in infected participants (p < 0.
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