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Characterization and Pathogenicity of Isolated from Rainbow Trout () in Korea.
Microorganisms
October 2023
Department of Aquatic Life Medicine, College of Fisheries Science, Pukyong National University, Busan 48513, Republic of Korea.
is the causative agent of bacterial cold-water disease in salmonids and rainbow trout fry syndrome. This pathogen has attained a global presence and can spread both horizontally and vertically. However, it was not documented in Korea before September 2018.
View Article and Find Full Text PDFA Preliminary Study on the Concentration of Oxytetracycline and 4-Epi-Oxytetracycline in Sow Milk.
Molecules
May 2022
Center of Translational Medicine, Faculty of Veterinary Medicine, Warsaw University of Life Sciences, Nowoursynowska 100, 02-787 Warsaw, Poland.
Even though modern analytical chemistry has developed a methodology enabling evaluation of the presence of OTC in milk, data regarding its concentration in the material collected from lactating sows are missing. Therefore, this paper was intended to provide new data on the transmission of OTC and its epimer, 4-epi-oxytetracycline (4-epi-OTC), in the milk of lactating sows after a singular intramuscular administration of a long-acting form of the antibiotic. The determination of OTC and 4-epi-OTC was carried out using ultrahigh-performance liquid chromatography with mass spectrometry (UHPLC-MS/MS).
View Article and Find Full Text PDFPharmacokinetics of oxytetracycline long-acting on plasma and semen of beef bulls.
Theriogenology
July 2022
Department of Veterinary Medical Sciences, University of Bologna, Ozzano dell'Emilia, Bologna, Italy; AUB-INFA, National Institute of Artificial Insemination, University of Bologna, Cadriano, Bologna, Italy.
The objectives of this investigation were to evaluate the pharmacokinetic parameters of oxytetracycline long-acting in plasma and seminal plasma after a single administration through either subcutaneous or intramuscular route at 10 mg/kg or 20 mg/kg dose. Four Simmental bulls, healthy and satisfactory potential breeders, were used. The route of administration either subcutaneous or intramuscular did not affect the mean values for 10 mg/kg dose in plasma (1,470 ng/mL vs.
View Article and Find Full Text PDFEvaluation of the use of ketoprofen for the treatment of digital dermatitis in dairy cattle: A randomised, positive controlled, clinical trial.
Vet Rec
March 2022
Department of Livestock and One Health, Veterinary and Ecological Sciences, Institute of Infection, University of Liverpool, Liverpool, UK.
Background: The objective of this study was to evaluate the benefits of administering ketoprofen to cows suffering from active digital dermatitis (DD).
Methods: 158 cows presented with active DD (M1, M2 or M4.1 stage) were randomly allocated to either the control or the treatment group.
Development and Application of an Interactive Physiologically Based Pharmacokinetic (iPBPK) Model to Predict Oxytetracycline Tissue Distribution and Withdrawal Intervals in Market-Age Sheep and Goats.
Toxicol Sci
September 2021
Institute of Computational Comparative Medicine (ICCM), Department of Anatomy and Physiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas 66506, USA.
Oxytetracycline (OTC) is a widely used antibiotic in food-producing animals. Extralabel use of OTC is common and may lead to violative residues in edible tissues. It is important to have a quantitative tool to predict scientifically based withdrawal intervals (WDIs) after extralabel use in food animals to ensure human food safety.
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