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Murine typhus: a re-emerging rickettsial zoonotic disease.

J Vector Ecol

December 2024

Urban and Public Health Entomology Program, Department of Agricultural Science and Plant Protection, Mississippi State University, Mississippi State, MS 39762 U.S.A.

Murine typhus, caused by , is re-emerging in many parts of the world. The disease is also called endemic typhus to differentiate from epidemic typhus (caused by ), and sometimes also named flea-borne typhus. Occasionally, literature sources will include as a causative agent of flea-borne typhus, but illnesses caused by are actually flea-borne spotted fever.

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The on-Site Monitoring and Specimen-Making of Ectoparasites on Rodents and Other Small Mammals.

Bio Protoc

November 2024

Institute of Entomology, Guizhou University, and the Provincial Key Laboratory for Agricultural Pest Management in Mountainous Region, Guiyang, China.

Article Synopsis
  • * Collecting and preparing specimens of these ectoparasites is critical for studying their classification, ecology, and epidemiology, as well as for monitoring disease vectors.
  • * The protocol details methods for on-site collection, fixation, and identification of ectoparasites, along with indices for monitoring host density and infestation levels, providing a thorough framework for research and control efforts.
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Lipidomic profiling of amniotic fluid reveals aberrant fetal lung development and fetal growth disrupted by lipid disorders during gestational asthma.

J Pharm Biomed Anal

January 2025

Jiangsu Key Laboratory of Children's Health and Chinese Medicine, Nanjing University of Chinese Medicine, Nanjing 210023, China; Medical Metabolomics Center, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address:

Article Synopsis
  • A study examined how maternal asthma during pregnancy affects fetal lung development by altering lipid metabolism in the amniotic fluid using a rat model exposed to house dust mites (HDM).
  • The research found that maternal asthma increased inflammatory markers in the fetuses and identified 18 abnormal lipids associated with oxidative stress, which impaired lung development.
  • It suggests that restoring normal lipid metabolism might be a potential treatment strategy for supporting fetal lung development in mothers with asthma.
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The topic of ragweed pollen (RW) versus house dust mites (HDMs) has often been deliberated, but the increasing incidence of co-sensitization between them has been scarcely addressed. Utilizing rats, we explored the effects of co-sensitization with the combination of HDMs and RW pollen extracts in correlation with high-fructose diet (HFrD) by in vitro tracheal reactivity analysis in isolated organ bath and biological explorations. Our findings unveiled interrelated connections between allergic asthma, dyslipidemia, and HFrD-induced obesity, shedding light on their compounding role through inflammation.

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The Distribution and Host-Association of the Vector Chigger Species in Southwest China.

Insects

July 2024

Institute of Pathogens and Vectors, Yunnan Provincial Key Laboratory for Zoonosis Control and Prevention, Dali University, Dali 671000, China.

Article Synopsis
  • A study from Southwest China (2001-2022) found that a species of chigger mite, known to transmit scrub typhus, infested a wide range of small mammals, particularly rodents.
  • A total of 2,161 mites were identified from 218 small mammal hosts, with the Asian house rat being the most common host, making up nearly 50% of the findings.
  • The study revealed that the susceptibility to mite infestation varied significantly among different small mammals and was influenced by environmental factors like altitude and latitude, suggesting that these mites could increase the risk of scrub typhus transmission.
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