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Lipid Profile, PCSK9, ANGPTL3 and Lipoprotein (a) Levels in Men Diagnosed With Localized High-Grade Prostate Cancer and Men At-Risk of Prostate Cancer.
Cancer Med
February 2025
Oncology Research Axis, Centre de Recherche du CHU de Québec-Université Laval, Quebec City, Quebec, Canada.
Background: Some cancers have been found to require abundant supplies of lipids for their development. One example is prostate cancer (PCa). To date, lipid-modifying factors, such as proprotein convertase subtilisin/kexin type 9 (PCSK9), angiopoietin-like 3 protein (ANGPTL3), and lipoprotein(a) or Lp(a), have not been reported in men with PCa.
View Article and Find Full Text PDFImproving cardiometabolic risk factors in Aboriginal and Torres Strait Islander people in northeast Arnhem Land: single arm trial of a co-designed dietary and lifestyle program.
Med J Aust
January 2025
Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, VIC.
Objective: To evaluate the impact of a 4-month dietary and lifestyle program co-designed and led by Aboriginal and Torres Strait Islander people on weight and metabolic markers, diet, and physical activity in overweight and obese adults in a remote Indigenous community.
Study Design: Single arm, pre-post intervention study.
Setting, Participants: Adult residents (18-65 years) of a remote Northern Territory community with body mass index (BMI) values of at least 25 kg/m or waist circumferences exceeding 94 cm (men) or 80 cm (women).
CAVIN-2 positively correlates with diabetic PAD and promotes LDL transcytosis by inhibiting eNOS activation.
Ann Med
December 2025
Department of Endocrinology, Institute of Geriatric Medicine, Liyuan Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
Objective: Caveolae are closely linked to the onset and progression of atherosclerosis. The pivotal involvement of caveolin-1 (CAV1) within the caveolae in atherosclerosis development has been consistently supported. However, the potential contributions of additional caveolae proteins to atherosclerosis necessitate further exploration.
View Article and Find Full Text PDF[The effectiveness of wellness programs in correcting risk factors for atherosclerosis in a sanatorium].
Vopr Kurortol Fizioter Lech Fiz Kult
January 2025
Bashkir State Medical University, Scientific Research Institute of Restorative Medicine and Balneology, Ufa, Russia.
Unlabelled: Atherosclerosis is the main cause of mortality and disability in the adult population. One of the reasons for the high mortality from atherosclerosis is the lack of effective measures to prevent cardiovascular complications that ensure timely detection and correction of risk factors for the development of atherosclerosis, primarily lipid metabolism disorders with high values of proatherogenic lipids. In the restorative correction of dyslipidemia, the most promising is the use of health programs based on therapeutic physical factors, the combined use of natural (mineral waters, kumiss, climate) with physical training, training in health schools, with their implementation in sanatorium-resort conditions.
View Article and Find Full Text PDF[Assessment of the clinical effectiveness of a specialized fermented milk product for the dietary correction of carbohydrate and fat metabolism disorders].
Vopr Pitan
January 2025
Limited Liability Company "Pyatigorsk Dairy Plant", 357500, Pyatigorsk, Russian Federation.
To level out the nutrient imbalance in diets, patients with carbohydrate and lipid metabolism disorders are prescribed to include specialized low-fat food with increased protein content. In this regard, the development and evaluation of the effectiveness of such products enriched with micronutrients is relevant. of the research was to evaluate the clinical effectiveness of a specialized fermented milk product for the dietary correction of carbohydrate and fat metabolism disorders.
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