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http://dx.doi.org/10.1097/00000658-195604000-00017 | DOI Listing |
Small
January 2025
Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247667, India.
Cells perceive external and internally generated forces of different kinds, significantly impacting their cellular biology. In the relatively nascent field of mechanobiology, the impact of such forces is studied and further utilized to broaden the knowledge of cellular developmental pathways, disease progression, tissue engineering, and developing novel regenerative strategies. However, extensive considerations of mechanotransduction pathways for biomedical applications are still broadly limited due to a lack of affordable technologies in terms of devices and simple magnetic actuatable materials.
View Article and Find Full Text PDFBull Math Biol
January 2025
School of Mathematical Sciences, Queensland University of Technology (QUT), Brisbane, Australia.
We propose a simple mathematical model to describe the mechanical relaxation of cells within a curved epithelial tissue layer represented by an arbitrary curve in two-dimensional space. This model generalises previous one-dimensional models of flat epithelia to investigate the influence of curvature for mechanical relaxation. We represent the mechanics of a cell body either by straight springs, or by curved springs that follow the curve's shape.
View Article and Find Full Text PDFMater Horiz
January 2025
State Key Laboratory of New Textile Materials and Advanced Processing Technologies, Wuhan Textile University, Wuhan 430200, China.
Adaptive control of solar light based on an optical switching strategy is essential to tune thermal gain, while real-time solar regulation and hence on-demand thermal management coupled with dynamic conditions still faces a formidable challenge. Herein, we develop a stacking structure which is mechanosensitive and can be finely tuned depending on the dynamic cavitation effect. Specifically, the stacking structure transfers from a solid monolith state to porous layered state progressively under mechanical stretching, and the resulting porous layered state gradually goes back to the solid monolith state once the load is released.
View Article and Find Full Text PDFJ Acoust Soc Am
January 2025
Department of Mechanical Engineering, Binghamton University, Binghamton, New York 13902, USA.
A study is presented of a method for creating an acoustic flow sensor that is generally compatible with current silicon microfabrication processes. An aim of this effort is to obtain a design consisting of a minimal departure from the existing designs employed in mass-produced silicon microphones. Because the primary component in all of these microphones is the cavity behind the pressure-sensing diaphragm, we begin with a study of the acoustic particle velocity within a cavity in a planar surface.
View Article and Find Full Text PDFIntensive Care Med
January 2025
Critical Care Medicine, Complejo Hospitalario Universitario de Toledo, Toledo, Spain.
Purpose: Predicting extubation failure remains a clinical challenge. This study aimed to determine diagnostic accuracy of models used at the bed side.
Methods: Post hoc analysis of 2341 patients at all risk included in five multicenter randomized trials.
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