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| http://dx.doi.org/10.1128/jb.71.2.217-222.1956 | DOI Listing |
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The first five years of implementing Missouri's medication first approach to opioid use disorder treatment: Plateaus, regressions, and underbellies of progress.
J Subst Use Addict Treat
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University of Missouri-St. Louis, Addiction Science, Missouri Institute of Mental Health, 1 University Blvd., Benton Hall, Room 206, St. Louis, MO 63121, USA.
Introduction: Missouri's Medication First ("MedFirst") approach promotes same-day and long-term low-threshold access to medications for opioid use disorder (MOUD). Since 2017, Missouri's SAMHSA-funded State Targeted and State Opioid Response (STR/SOR) grants have supported MedFirst services (both medical and psychosocial) for uninsured individuals with opioid use disorder at state-contracted treatment programs. Though MedFirst demonstrated early success, results - with attention to possible racial disparities - must be revisited after five years of implementation.
View Article and Find Full Text PDFCharacterization of gelatin-based composite films loaded with polysaccharide and carbon dots from Stropharia rugosoannulata and their application in pork fresh-keeping.
Int J Biol Macromol
January 2025
Faculty of Food Science and Engineering, Kunming University of Science and Technology, Kunming 650500, China. Electronic address:
In this study, bio-based composite films with enhanced barrier, mechanical, antioxidant and antimicrobial properties were prepared by incorporating Stropharia rugosoannulata waste (SP)-derived polysaccharides (SPP) and carbon dots (SPCDs) as an active substance into gelatin (GEL) matrix, which were evaluated for their potential application in pork preservation. The effects of varying concentrations of SPCDs on the morphology, microstructure, and overall performance of the films were systematically investigated. The findings demonstrated that the addition of SPCDs to the GEL/SPP matrix significantly improved the mechanical strength, water vapor permeability, and ultraviolet light blocking ability of the composite films.
View Article and Find Full Text PDFFocused Ultrasound Neuromodulation: Exploring a Novel Treatment for Severe Opioid Use Disorder.
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Department of Neuroscience, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA; Department of Behavioral Medicine and Psychiatry, Rockefeller Neuroscience Institute, West Virginia University, Morgantown, WV, USA. Electronic address:
Background: Opioid use disorder remains a critical healthcare challenge as current therapeutic strategies have limitations resulting in high recurrence and deaths. We evaluated safety and feasibility of focused ultrasound (FUS) neuromodulation to reduce substance cravings and use in severe opioid- and co-occurring substance use disorders.
Methods: This prospective, open-label, single-arm study enrolled 8 participants with severe, primary opioid use disorder with co-occurring substance use.
Leveraging almost hydrophobic PVDF membrane and in-situ ozonation in O/UF/BAC system for superior anti-fouling and rejection performance in drinking water treatment.
Water Res
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State Key Joint Laboratory of Environment Simulation and Pollution Control, School of Environment, Tsinghua University, Beijing 100084, China. Electronic address:
The almost hydrophobic PVDF membrane (PVDF matrix) commonly exhibited excellent performance in pollutant rejection but with poor anti-fouling performance. This study intended to develop the rejection performance and enhance anti-fouling of the PVDF membrane in an O/UF/BAC system for high quality water production through leveraging the advantages of in-situ ozonation and the nature of the PVDF membrane. Reduced density gradient (RDG) analysis demonstrated that the PVDF membrane exhibited excellent ozone resistance by reducing hydrogen bonds and electrostatic interactions between the membrane surface and ozone.
View Article and Find Full Text PDFSystematic Review on Chemsex: Advocating for Inclusive Research and Primary Prevention.
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Faculty of Health Sciences, Valencian International University, Pintor Sorolla 21, 46002, Valencia, Spain.
Chemsex is a specific practice of sexualized drug use (SDU), linked mainly to the group of men who have sex with men (MSM). This practice has become a public health problem due to the increase in sexually transmitted infections and HIV. However, there are groups and aspects that require greater visibility and research.
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