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Leukocytoclastic vasculitis in a patient with syphilis and HIV coinfection.
Rev Inst Med Trop Sao Paulo
October 2022
Universidad del Rosario , Bogotá , Colombia.
Leukocytoclastic vasculitis (LCV) is a small vessel vasculitis characterized by an inflammatory infiltrate composed of neutrophils with fibrinoid necrosis and "leukocytoclasia", a term that refers to nuclei disintegration into fragments. LCV is related to multiple conditions including ANCA-associated vasculitis, cryoglobulinemia, IgA vasculitis, infectious and systemic diseases such as rheumatoid arthritis and systemic erythematous lupus (SLE) as well as infections and malignancy. We describe the clinical case of severe systemic vasculitis in a young male patient with secondary syphilis and HIV coinfection manifested by cutaneous and neurological involvement, as well as peripheral necrosis that requires bilateral lower limb amputation.
View Article and Find Full Text PDFLeft Ventricular Giant Aneurysm Caused by Congenital Syphilis Causing Severe Outflow Tract Obstruction.
Ann Thorac Surg
January 2023
Department of Internal Medicine, College of Health Sciences, Addis Ababa University, Addis Ababa, Ethiopia.
We present the exceedingly rare case of an 18-year-old boy with recurrent syncope attacks and dyspnea at rest for 3 weeks. Transthoracic echocardiography showed a giant aneurysm dilatation occupying the left ventricular outflow tract. The intraoperative finding was a giant thick-walled unruptured aneurysm of the sinus of Valsalva from the right coronary cusp.
View Article and Find Full Text PDFCutaneous lymphocytic thrombophilic (macular) arteritis.
Clin Dermatol
November 2021
CTA Pathology and Departments of Dermatology and Pathology, Oregon Health and Science University, Portland, Oregon, USA.
Macular arteritis (MA) has a striking discordance between the clinical presentation of hyperpigmented macules and the histopathologic findings of a lymphocytic arteritis with intraluminal hyalinized fibrin ring and thrombosis. It has been proposed that MA represents the chronic, indolent, lymphocytic form of the neutrophil-predominant cutaneous polyarteritis nodosa. MA usually affects middle-aged women asymptomatically on the legs.
View Article and Find Full Text PDFColostomy stenosis due to chronic radiation enteritis. Report of clinical case.
Cir Cir
September 2021
Servicio de Cirugía General y del Aparato Digestivo, Hospital Clínico Universitario de Zaragoza, Instituto de Investigación Sanitaria Aragón (IIS Aragón). Zaragoza, España.
Antecedentes: La colitis actínica es una endarteritis obliterante ocasionada por exposición a radiación ionizante. Se manifiesta de manera aguda (primeras semanas) o crónica (hasta 30 años después).
Caso ClÍnico: Paciente tratado por neoplasia rectal mediante quimiorradioterapia y amputación abdominoperineal.
Syphilitic Pulmonary Inflammatory Pseudotumor: A Diagnostic Challenge.
Int J Surg Pathol
February 2021
University of Cape Town, Cape Town, South Africa.
A 46-year-old man presented with nonproductive cough and lower limb swelling. Chest radiograph showed a left lower lobe lung mass and multiple subpleural nodules. Other investigations revealed that he had nephrotic syndrome.
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