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Protective effects of Mycobacterium vaccae ATCC 15483 against "Western"-style diet-induced weight gain and visceral adiposity in adolescent male mice.

Brain Behav Immun

December 2024

Department of Integrative Physiology, University of Colorado Boulder, Boulder, CO 80309, USA; Department of Psychology and Neuroscience, University of Colorado Boulder, Boulder, CO 80309, USA; Center for Microbial Exploration, University of Colorado Boulder, Boulder, CO 80309, USA; Center for Neuroscience, University of Colorado Boulder, Boulder, CO 80309, USA; Department of Physical Medicine and Rehabilitation and Center for Neuroscience, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA. Electronic address:

The prevalence of noncommunicable inflammatory disease is increasing in modern urban societies, posing significant challenges to public health. Novel prevention and therapeutic strategies are needed to effectively deal with this issue. One promising approach is leveraging microorganisms such as Mycobacterium vaccae ATCC 15483, known for its anti-inflammatory, immunoregulatory, and stress-resilience properties.

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Cannabinoids for treating psychiatric disorders in youth: a systematic review of randomized controlled trials.

Child Adolesc Psychiatry Ment Health

December 2024

University Hospital of Child and Adolescent Psychiatry and Psychotherapy, University of Bern, Bern, Switzerland.

Article Synopsis
  • The systematic review investigates the effectiveness of cannabinoids for treating psychiatric disorders in individuals aged 0-25, synthesizing data from randomized placebo-controlled trials.
  • The analysis included 8 clinical trials with 474 participants, revealing a modest overall positive effect for symptom improvement, particularly in studies focusing on autism spectrum disorder.
  • Adult participants exhibited greater effects from cannabinoid treatment compared to younger populations, with both whole plant and pharmaceutical preparations showing similar efficacy.
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Unintended consequences of measures implemented in the school setting to contain the COVID-19 pandemic: a scoping review.

Cochrane Database Syst Rev

December 2024

Institute for Medical Information Processing, Biometry and Epidemiology - IBE, Chair of Public Health and Health Services Research, LMU Munich, Munich, Germany.

Background: Throughout the COVID-19 pandemic, schools were a key setting for intervening with public health and social measures (PHSM) to reduce transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Consequently, there is a need to assess the varied unintended consequences associated with PHSM implemented in the school setting, for students, teachers, and school staff, as well as for families and the wider community. This is an update of a Cochrane scoping review first published in 2022.

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The overlooked burden of persistent physical symptoms: a call for action in European healthcare.

Lancet Reg Health Eur

January 2025

Department of Psychosomatic Medicine and Psychotherapy, Centre for Internal Medicine, University Medical Centre Hamburg-Eppendorf, Martinistraße 52, Hamburg 20246, Germany.

Regardless of their cause, persistent physical symptoms are distressing somatic complaints that occur on most days for at least several months. They are common in patients with somatic diseases, functional somatic disorders, mental disorders, and undiagnosed medical conditions and are often associated with significant impairment and medical costs. Despite their prevalence and impact, persistent physical symptoms are often overlooked in medical care.

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Perceived Changes in Anxiety Symptom Burden During Treatment with : A Prospective, Single-Arm Study.

Pharmaceuticals (Basel)

October 2024

Clinical Research Department, Klinik Arlesheim, 4144 Arlesheim, Switzerland.

Background/objectives: spp. preparations are widely used in Anthroposophic Medicine, most often for mental and behavioral disorders, including anxiety. Studies in animals revealed various anxiolytic and neurosedative effects for .

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