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Supramolecular cyclodextrin deep eutectic solvent-strengthened chitosan eutectogel as a novel percutaneous delivery system of resveratrol for anti-psoriasis.
Int J Biol Macromol
January 2025
School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China. Electronic address:
Psoriasis is a chronic and incurable inflammatory skin disease usually requiring long-term disease management. Natural phytochemical resveratrol (RES) has been known for high efficiency and low toxicity, exhibiting good anti-psoriasis potential. However, its biological activity is limited by poor solubility, chemical instability, and insufficient skin retention.
View Article and Find Full Text PDFEffects of topical neutral protamine Hagedorn insulin on corneal wound healing: an experimental study in rabbits.
Biotech Histochem
January 2025
Faculty of Veterinary Medicine, Department of Pathology, Siirt University, Siirt, Turkiye.
Corneal injuries are common in human and veterinary ophthalmology. There are many studies which have investigated the treatment of corneal epithelial defects. This study aimed to investigate the effects of Neutral Protamine Hagedorn (NPH) insulin as an ointment for wound healing in experimental corneal defects.
View Article and Find Full Text PDFPatients presenting with severe acute cardiogenic pulmonary edema with hypoxia commonly require intubation until heart failure treatments take effect. A new term describing similar condition is called sympathetic crashing acute pulmonary edema (SCAPE). It is also called Flash pulmonary edema.
View Article and Find Full Text PDFHerpetic Endotheliitis Induced Interface Fluid Syndrome 16 years After Laser in Situ Keratomileusis.
Cornea
January 2025
Cornea Service, Wills Eye Hospital, Philadelphia, PA.
Purpose: To report a case of herpes simplex virus (HSV) endotheliitis inducing acute interface fluid syndrome in a patient with a remote history of laser in situ keratomileusis (LASIK).
Methods: Case report and literature review.
Results: A 51-year-old man with a history of LASIK 16 years prior presented with unilateral HSV endotheliitis and was found to have acute interface fluid syndrome secondary to endothelial decompensation.
Dry crude pomegranate peel extract as a bio-input for medicinal pharmaceutical gel with healing activity.
Chem Biodivers
January 2025
UFES: Universidade Federal do Espirito Santo, Center of Exact, Natural and Health Sciences, Alto Universitário, Alegre, BRAZIL.
The sustainable use of pomegranate peel, a by-product of the food industry, is gaining importance in developing pharmaceutical bio-inputs, aligning with circular economy practices and waste reduction. This study explores the application of dry crude pomegranate peel extract (PPE) as a bio-input for medicinal gels with wound healing properties. PPE was extracted via percolation in ethanol and freeze-dried.
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