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Comparison of Two Synthesis Methods for 3D PLA-Ibuprofen Nanofibrillar Scaffolds.
Pharmaceutics
January 2025
Programa de Posgrado en Odontología, Universidad de Costa Rica, Ciudad Universitaria Rodrigo Facio, San Jose 11501-2060, Costa Rica.
Objectives: This study aimed to synthesize polylactic acid (PLA) nanofibrillar scaffolds loaded with ibuprofen (IBU) using electrospinning (ES) and air-jet spinning (AJS). The scaffolds were evaluated for their physicochemical properties, drug release profiles, and biocompatibility to assess their potential for local analgesic applications.
Methods: Solutions of 10% (/) PLA combined with IBU at concentrations of 10%, 20%, and 30% were processed into nanofibrillar membranes using ES and AJS.
Preliminary Study by Differential Scanning Calorimetric Analysis of Red Blood Cells in Peripheral Artery Disease Patients Treated with Cilostazol: Correlation with Improvements in Walking Distance.
Pharmaceuticals (Basel)
January 2025
Department of Vascular Surgery, Medical School, University of Pécs, H-7624 Pécs, Hungary.
: Peripheral artery disease (PAD) is a prevalent vascular condition characterized by arterial narrowing, which impairs blood flow and manifests as intermittent claudication, a pain or cramping sensation induced by physical activity or ambulation. Walking distance is a crucial clinical indicator of peripheral artery disease, and it correlates with the disease severity and risk of mortality. It reflects the severity of the disease, with reduced mobility indicating an increased risk of morbidity.
View Article and Find Full Text PDFEffect of Planting Systems on the Physicochemical Properties and Bioactivities of Strawberry Polysaccharides.
Foods
January 2025
College of Food Science and Engineering, Guiyang University, Guiyang 550005, China.
Suitable planting systems are critical for the physicochemical and bioactivities of strawberry ( Duch.) polysaccharides (SPs). In this study, SPs were prepared through hot water extraction, and the differences in physicochemical characteristics and bioactivities between SPs derived from elevated matrix soilless planting strawberries (EP-SP) and those from and conventional soil planting strawberries (GP-SP) were investigated.
View Article and Find Full Text PDFThermodynamics insights of lignin dissolution in deep eutectic solvents.
Int J Biol Macromol
January 2025
Beijing Key Laboratory of Lignocellulosic Chemistry, State Key Laboratory of Efficient Production of Forest Resources Beijing Forestry University, Beijing 100083, China. Electronic address:
To develop a green solvent for lignin dissolution, the most fundamental aspects of its mechanism must be elucidated. Understanding the thermodynamic behaviors is of significant importance for designing novel deep eutectic solvents (DESs) to dissolve lignin. Herein, the heat of dissolution of lignin in acidic, alkaline or neutral DESs was determined by high-precision solution microcalorimetry, and comprehensively investigated the effect of physicochemical properties of DESs on the heat of dissolution and solubility of lignin.
View Article and Find Full Text PDFIsolation and ultrasonication of pearl millet protein: Effect on techno-functional, structural, molecular interaction, and rheological properties.
Food Res Int
February 2025
Department of Food Science and Technology, Punjab Agricultural University, Ludhiana, Punjab 141 004, India. Electronic address:
In the present study, the impact of ultrasonication treatment (US) at varying time duration (10 and 20 min) on pearl millet protein (PMP) was evaluated. The native and ultrasonicated PMP were evaluated for techno-functional properties, zeta potential, particle size, SEM, FTIR, thermal properties and dynamic rheology. The significant (p < 0.
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