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Postnatal development of vasoactive intestinal polypeptide-expressing GABAergic interneurons in mouse somatosensory cortex.
Acta Physiol (Oxf)
February 2025
Institute for Physiology, University Medical Centre of the Johannes Gutenberg University Mainz, Mainz, Germany.
Aim: Despite dysfunctional vasoactive intestinal polypeptide-positive interneurons (VIP-INs) being linked to the emergence of neurodevelopmental disorders, the temporal profile of VIP-IN functional maturation and cortical network integration remains unclear.
Methods: Postnatal VIP-IN development was traced with patch clamp experiments in the somatosensory cortex of Vip-IRES-cre x tdTomato mice. Age groups were chosen during barrel field formation, before and after activation of main sensory inputs, and in adult animals (postnatal days (P) P3-4, P8-10, P14-16, and P30-36).
Deciphering the colostral-immunity transfer: from mammary gland to neonates small intestine.
Vet Res Commun
January 2025
Laboratory of Agricultural Animal Genetics, Breeding and Reproduction of Ministry of Education, Huazhong Agricultural University, Wuhan, China.
Colostrum, the initial mammary secretion produced by various mammals following birth, is a conduit for maternal immunity transfer in diverse mammalian species. Concurrently, many cellular processes are occurring in the neonatal small intestine to prepare it to receive molecular signals from a superfood essential for the neonate's health and development. During the prepartum colostrum secretion, the newborn intestine undergoes transient alterations in the intestinal barrier, primarily regulating immunoglobulin absorption.
View Article and Find Full Text PDFReducing Dust and Respirable Crystalline Silica Near Conveyors Using a Hybrid Dust Control System.
Min Metall Explor
November 2024
Miller Consulting, Spokane, WA, USA.
Occupational exposures to respirable dusts and respirable crystalline silica (RCS) is well established as a health hazard in many industries including mining, construction, and oil and gas extraction. The U.S.
View Article and Find Full Text PDFBiosecurity and Biocontainment for Ruminant Respiratory Disease.
Vet Clin North Am Food Anim Pract
January 2025
Department of Veterinary and Biomedical Sciences, Animal Disease Research and Diagnostic Laboratory, South Dakota State University, Brookings, SD 57007, USA.
Respiratory disease in cattle and small ruminants is caused by various factors, including inadequate biosecurity and biocontainment. Biosecurity and biocontainment depend on good husbandry. Testing on arrival and quarantining for 42 to 56 days could improve biosecurity.
View Article and Find Full Text PDFGenetic associations of colostrum yield with antibodies concentration and gross composition for selective breeding in Italian Holsteins.
J Dairy Sci
January 2025
Department of Agronomy, Food, Natural resources, Animals and Environment, University of Padova, Viale dell'Università 16, 35020 Legnaro (PD), Italy.
The quality of bovine colostrum, primarily determined by IgG concentration, is essential for the transfer of passive immunity and the development of the gastrointestinal tract in neonates. High IgG concentration in bovine colostrum (BC) is pivotal for the calf at first meal; however, while neonates often refuse to voluntarily drink the recommended amount of BC in the first hours of life, the dam frequently fails to produce a sufficient volume of colostrum at first milking. This study seeks to estimate the h of colostrum yield (CY) and its genetic correlations with total Ig, IgG, protein, and fat concentrations for the first time in the Italian Holstein population.
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