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Spinal cord injury in abusive and accidental head injury in children, a neuropathological investigation.
Int J Legal Med
January 2025
London Neurodegenerative Diseases Brain Bank, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
The diagnosis of abusive head trauma (AbHT) in children is a challenging one that needs to be differentiated from natural disease and accidental head injury (AcHT). There is increasing evidence from the Neuroradiology field showing spinal cord injury in children subject to AbHT, which has, so far, been poorly investigated pathologically. In this study we retrospectively reviewed the forensic records of 110 paediatric head injury cases over an eight-year-period.
View Article and Find Full Text PDFCentral nervous system vascular complications associated with the acute form of steroid-responsive meningitis-arteritis.
Vet J
January 2025
Departament de Medicina i Cirurgia Animals, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Barcelona 08193, Spain; Fundació Hospital Clínic Veterinari, Facultat de Veterinària, Universitat Autònoma de Barcelona, Bellaterra, Barcelona 08193, Spain. Electronic address:
This retrospective study aims to describe the vascular events in the central nervous system (CNS) associated with the acute form of steroid-responsive meningitis-arteritis (SRMA), to compare the clinical features of dogs with and without such complications and to potentially identify predisposing factors for these events. Dogs with a presumptive diagnosis of SRMA visited between 2018 and 2023 with full medical records that underwent neurological examination, blood testing, cervical computed tomography or magnetic resonance imaging and cerebrospinal fluid (CSF) analysis were included. Thirty-three dogs were included and divided in two groups.
View Article and Find Full Text PDFFat droplets in the cerebrospinal fluid (CSF) spaces of the brain.
AIMS Neurosci
November 2024
Clinical Sciences, California Northstate University College of Medicine, Elk Grove, CA, USA.
It is rare to find free floating fat droplets in the cerebral spinal fluid (CSF) spaces of the brain. When fat droplets are seen in the CSF spaces, the most common cause is the rupture of a dermoid cyst. Dermoid cysts are congenital inclusion cysts that form during the neural tube closure between the third and fifth weeks of embryogenesis.
View Article and Find Full Text PDFUnderstanding the Measurement of Pressure Within the Spinal Cord to Optimize Spinal Cord Perfusion Pressure Using a Porcine Model of Spinal Cord Injury.
J Neurotrauma
January 2025
International Collaboration on Repair Discoveries (ICORD), University of British Columbia (UBC), Vancouver, Canada.
Recent studies have reported that monitoring spinal cord perfusion pressure (SCPP) using a pressure probe to measure "intraspinal pressure" (ISP) within the subdural space at the injury site may improve the hemodynamic management of acute spinal cord injury (SCI) patients. This study aimed to investigate, within a pig model of SCI, the relationship between the ISP measured within the subdural space and the "spinal cord pressure" (SCP) measured within the spinal cord itself. Specifically, we sought to characterize the changes to ISP and SCP over time, both rostral and caudal to the injury epicenter, and in relation to native spinal cord morphometry.
View Article and Find Full Text PDFIncidental asymptomatic spinal cerebrospinal fluid leaks: single-center experience, and a presentation of seven cases.
J Neurointerv Surg
December 2024
Neurology, Mayo Clinic in Florida, Jacksonville, Florida, USA
Background: The majority of patients with spontaneous intracranial hypotension (SIH) are symptomatic. Some patients are discovered incidentally. The proportion of asymptomatic SIH has never been defined.
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