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Difficulty score for the treatment of multiple gingival recessions with the Modified Coronally Advanced Tunnel technique: a preliminary reliability study.
Clin Oral Investig
January 2025
Department of Biomedical and Neuromotor Sciences, Bologna University, Piazza di Porta S. Donato St 2, 40-127, Bologna, Italy.
Objectives: The purpose of this study was to propose a new difficulty score for the treatment of multiple gingival recessions (GRs) with Modified Coronally Advanced Tunnel (MCAT), and to test the score's reliability.
Material And Methods: A difficulty score was developed for the assessment and grading of 13 relevant anatomical parameters at baseline. Six experienced dental practitioners evaluated existing GRs in three patients.
Curcumin-Loaded Lipid Nanoparticles: A Promising Antimicrobial Strategy Against in Endodontic Infections.
Pharmaceutics
January 2025
Laboratório Associado para a Química Verde-Rede de Química e Tecnologia (LAQV, REQUIMTE), Instituto de Ciências Biomédicas de Abel Salazar, Universidade do Porto, Rua de Jorge Viterbo Ferreira 228, 4050-313 Porto, Portugal.
This study aims to evaluate the efficacy of curcumin (CUR), a natural polyphenol with potent antimicrobial and anti-inflammatory properties, when formulated as solid lipid nanoparticles (CUR-loaded SLN) against . Solid lipid nanoparticles (SLNs) were prepared as a carrier for CUR, which significantly improved its solubility. SLNs made with cetyl palmitate and Tween 80 were obtained via the hot ultrasonication method.
View Article and Find Full Text PDFA Preliminary Stability Assessment of Three State-of-the-Art CAD/CAM Materials Under Human Gingival Cell Culture.
Polymers (Basel)
January 2025
Plasma and Radiation Physics, National Institute for Laser, 077125 Magurele, Romania.
CAM/CAD composites are widely used as dental restoration materials due to their resistivity to wear. The purpose of this study was to determine the effect of human gingival fibroblast cells on three different computer-aided design/computer-aided manufacturing (CAD/CAM) hybrid materials with resin-based composites (RBC) and to assess their stability following cell growth. The CAM/CAD dental materials were investigated in different conditions as follows: (i) cells (human gingival fibroblasts, HFIB-Gs) incubated over the material for each sample, denoted as A; (ii) reference, the raw material, denoted as B; and (iii) materials incubated in DMEM medium, denoted as C.
View Article and Find Full Text PDFProbiotic Therapy as an Adjuvant in the Treatment of Periodontal Disease: An Innovative Approach.
Medicina (Kaunas)
January 2025
Department of Dental Medicine, Faculty of Medicine and Pharmacy, University of Oradea, 10 1st Decembrie Street, 410073 Oradea, Romania.
: Periodontal inflammation, often linked to oral microbiota dysbiosis dominated by pathogenic bacteria, remains a significant challenge in periodontitis management. Traditional periodontal therapies primarily reduce the bacterial load but fail to restore the microbiota balance. Probiotics offer a promising therapeutic adjunct with their ability to enhance beneficial bacteria.
View Article and Find Full Text PDFEffects of Insulin-like Growth Factor 1 on the Maintenance of Cell Viability and Osteogenic Differentiation of Gingiva-Derived Mesenchymal Stem Cell Spheroids.
Medicina (Kaunas)
January 2025
Department of Periodontics, College of Medicine, The Catholic University of Korea, Seoul 06591, Republic of Korea.
Insulin-like growth factor-1 (IGF-1) plays a vital role in various cellular processes, including those involving stem cells. This study evaluated the effects of IGF-1 on cell survival, osteogenic differentiation, and mRNA expression in gingiva-derived mesenchymal stem cell spheroids. Using concave microwells, spheroids were generated in the presence of IGF-1 at concentrations of 0, 10, and 100 ng/mL.
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