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Article Synopsis
  • The main non-traumatic causes of acute single-joint pain include microcrystalline, degenerative, reactive, and septic arthritis, with septic arthritis needing quick exclusion through joint effusion puncture.
  • If there’s no sepsis, surgical drainage should be done within 24 hours of admission.
  • For conditions like gout and reactive arthritis, imaging and urate-lowering treatments are recommended, while osteoarthritis management emphasizes self-care strategies for pain relief.
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Emergencies in inflammatory rheumatic diseases.

Rheumatol Int

September 2024

Department of Physical Medicine and Rehabilitation, University of Health Sciences, Adana City Research and Training Hospital, Adana, Türkiye.

Inflammatory rheumatic diseases (IRDs), encompassing a broad spectrum of chronic disorders, typically necessitate prolonged therapeutic intervention. Nevertheless, these diseases can sometimes manifest as severe emergencies requiring prompt and extensive medical intervention. Urgent intervention is essential for effectively recognizing and managing these situations, as they have the potential to be life-threatening and can result in severe morbidity and mortality.

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Background: With their broad presentations and no global biomarker to discriminate crises and attack-free periods, Systemic Auto-Inflammatory Diseases (SAID) are difficult to manage. This study assessed Serum Amyloid A (SAA), C-reactive protein (CRP) and serum calprotectin as potential biomarkers to monitor patients with SAID.

Method: SAA (already studied in Familial Mediterranean Fever (FMF)), CRP and serum calprotectin were measured on SAID adult patients from Juvenile Inflammatory Rheumatism (JIR) cohort during their follow-up visits between 2020 and 2022.

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Inborn metabolic diseases (IMD) are rare conditions that can be diagnosed during adulthood. Patients with IMD may have joint symptoms and the challenge is to establish an early diagnosis in order to institute appropriate treatment and prevent irreversible damage. This review describes the joint manifestations of IMD that may be encountered in adults.

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The role of monocytes in thrombotic diseases: a review.

Front Cardiovasc Med

June 2023

Science and Education Department, Chengdu Xinhua Hospital, Chengdu, China.

Cardiovascular and cerebrovascular diseases are the number one killer threatening people's life and health, among which cardiovascular thrombotic events are the most common. As the cause of particularly serious cardiovascular events, thrombosis can trigger fatal crises such as acute coronary syndrome (myocardial infarction and unstable angina), cerebral infarction and so on. Circulating monocytes are an important part of innate immunity.

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