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Genetic Variants Affecting FADS2 Enzyme Dynamics and Gene Expression in Cogenetic Oysters with Different PUFA Levels Provide New Tools to Improve Unsaturated Fatty Acids.
Int J Mol Sci
December 2024
Laboratory for Marine Biology and Biotechnology, Qingdao Marine Science and Technology Center, Qingdao 266200, China.
Long-chain polyunsaturated fatty acids (LC-PUFAs) are crucial for human health and cannot be produced internally. Bivalves, such as oysters, serve as valuable sources of high-quality PUFAs. The enzyme fatty acid desaturase (FADS) plays a key role in the metabolism of LC-PUFAs.
View Article and Find Full Text PDFNeonatal Hypoglycemia and Neurodevelopmental Outcomes-An Updated Systematic Review and Meta-Analysis.
Life (Basel)
December 2024
Department of Neonatology, Emergency County Hospital Bihor, 410167 Oradea, Romania.
Background And Objective: The effects of neonatal hypoglycemia on the developing brain are well known, resulting in poor neurological outcomes. We aimed to perform an updated meta-analysis on neonatal hypoglycemia, the severity of hypoglycemia, and the associated neurodevelopmental outcomes from infancy to adulthood.
Methods: A systematic literature search was conducted from inception until March 2024, using the PubMed, CINAHL, Embase, and the CENTRAL databases.
Integrated transcriptomic and lipidomic analysis reveals that arachidonic acid mediates the allograft-induced stress response in Pinctada fucata martensii.
Comp Biochem Physiol Part D Genomics Proteomics
December 2024
Fisheries College, Guangdong Ocean University, Zhanjiang 524088, China; Guangdong Science and Innovation Center for Pearl Culture, Zhanjiang 524088, China; Pearl Breeding and Processing Engineering Technology Research Center of Guangdong Province, Zhanjiang 524088, China; Guangdong Provincial Key Laboratory of Aquatic Animal Disease Control and Healthy culture, Zhanjiang 524088, China. Electronic address:
This study investigated the protective effect of arachidonic acid (ARA) against the allograft-induced stress response in Pinctada fucata martensii by characterizing pearl production traits and changes in genes and lipids during postoperative care. Survival and pearl production traits were higher in the ARA treatment group (ARAG) than in the control group (CG). There were 1536 differentially expressed genes (DEGs) in CG-1d vs ARAG-1d and 833 DEGs in CG-3d vs ARAG-3d.
View Article and Find Full Text PDFMitigating oxidative stress in oyster larvae: Curcumin promotes enhanced redox balance, antioxidant capacity, development, and resistance to antifouling compounds.
Aquat Toxicol
December 2024
Univ Brest, Ifremer, CNRS, IRD, LEMAR, IUEM, F-29280 Plouzané, France. Electronic address:
Curcumin (CUR) is a natural compound recognized for stimulating the expression of antioxidant genes. This characteristic has been used to promote animal health and production in aquaculture settings. We hypothesized that supplementing embryos of Crassostrea gigas oysters with CUR would improve their antioxidant capacity, development, and resilience to stress.
View Article and Find Full Text PDFCharacterization of acetylcholinesterase and carboxylesterases in the mangrove oyster Crassostrea gasar as biomarkers of exposure to environmental pollutants.
Aquat Toxicol
December 2024
Laboratory of Biomarkers of Aquatic Contamination and Immunochemistry - LABCAI, Federal University of Santa Catarina, Florianópolis 88034-257, Brazil.
Brazil is one of the world's leading consumers of agricultural pesticides, highlighting the urgent need to identify responsive biomarkers as diagnostic and prognostic tools for monitoring aquatic pollution. Acetylcholinesterase (AChE) and carboxylesterases (CbE) are B-esterases enzymes expressed in several organisms. AChE plays an essential role in neural transmission at cholinergic synapses, while CbE are directly involved in the detoxification of organic pollutants, including organophosphorus pesticides.
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