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A novel machine learning based framework for developing composite digital biomarkers of disease progression.
Front Digit Health
January 2025
Biostatistics and Research Decision Sciences, Merck & Co., Inc., Rahway, NJ, United States.
Background: Current methods of measuring disease progression of neurodegenerative disorders, including Parkinson's disease (PD), largely rely on composite clinical rating scales, which are prone to subjective biases and lack the sensitivity to detect progression signals in a timely manner. Digital health technology (DHT)-derived measures offer potential solutions to provide objective, precise, and sensitive measures that address these limitations. However, the complexity of DHT datasets and the potential to derive numerous digital features that were not previously possible to measure pose challenges, including in selection of the most important digital features and construction of composite digital biomarkers.
View Article and Find Full Text PDFBibliometric Analysis of the Highest Cited Cosmetic Upper Facial Plastic Surgery Articles Over 50 Years.
Aesthet Surg J Open Forum
December 2024
In this bibliometric analysis, the authors analyze the top 100 (T100) most cited articles on cosmetic upper facial plastic surgery. Throughout this study, the objective of the authors is to delineate the trends in cosmetic upper facial surgeries to identify prevailing techniques, emerging trends, and potential areas of future investigation. The articles were indexed from the Web of Science database and were extracted in a double-blinded manner by 2 independent graders.
View Article and Find Full Text PDFEnhancing Cervical Foraminotomy Outcomes With Patient-Specific 3D Anatomical Models: A Comparative Study.
Cureus
December 2024
Diagnostic Radiology, University of Washington, Seattle, USA.
Introduction: Cervical foraminotomy is a procedure used to treat patients with radiculopathy. While the procedure can be performed using a minimally invasive technique, achieving complete visualization of relevant anatomy can be challenging. This study explores the use of patient-specific three-dimensional (3D) printed anatomical models, created from advanced medical imaging data, for preoperative planning and intraoperative guidance in cervical foraminotomy by comparing fluoroscopy time, operative time, estimated blood loss volume, and functional improvement.
View Article and Find Full Text PDFTechnological Advancements in Augmented, Mixed, and Virtual Reality Technologies for Surgery: A Systematic Review.
Cureus
December 2024
Private Practice, General Vascular Surgery Medical Group, Inc., San Leandro, USA.
Recent advancements in artificial intelligence (AI) have shown significant potential in the medical field, although many applications are still in the research phase. This paper provides a comprehensive review of advancements in augmented reality (AR), mixed reality (MR), and virtual reality (VR) for surgical applications from 2019 to 2024 to accelerate the transition of AI from the research to the clinical phase. This paper also provides an overview of proposed databases for further use in extended reality (XR), which includes AR, MR, and VR, as well as a summary of typical research applications involving XR in surgical practices.
View Article and Find Full Text PDFIncreasing Incidence of Pickleball Injuries Presenting to US Emergency Departments: A 10-year Epidemiologic Analysis of Mechanisms and Trends.
Orthop J Sports Med
January 2025
Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Background: Pickleball is one of the fastest-growing sports in the United States. It is popular among seniors but has recently grown across all age groups. As pickleball has gained interest, its corresponding injury burden has also increased.
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