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Objective: To report clinical outcomes of skeletally immature dogs with antebrachial deformities secondary to premature closure of the distal radial physis (PCDRP) treated with angular corrections and distraction osteogenesis using circular external skeletal fixation (CESF).

Study Design: Retrospective multi-institutional case series.

Animals: A total of 12 client-owned dogs with premature distal radial physeal closure.

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Introduction Atrial fibrillation (AF), the most common cardiac arrhythmia, poses challenges in predicting thromboembolic risk. While the CHADS-VASc (congestive heart failure, hypertension, age ≥ 75 years (doubled), type 2 diabetes mellitus, previous stroke, transient ischemic attack, or thromboembolism (doubled), vascular disease, age 65-74 years, and sex category) score remains essential, its limitations include failure to identify left atrial (LA) thrombus in some patients. Transesophageal echocardiography (TEE) provides superior detection of LA thrombi and thrombogenic factors compared to transthoracic echocardiography (TTE), improving risk stratification, especially in intermediate-risk groups.

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More than 1 million permanent pacemakers are implanted worldwide each year, half of which are in patients with high-grade atrioventricular block. Pacemakers provide adequate frequency support in the initial stage, but traditional right ventricular (RV) pacing may lead to or aggravate left ventricular dysfunction and arrhythmia. Several potential risk factors for heart failure and arrhythmias after pacemaker surgery have been identified, but their occurrence remains difficult to predict clinically.

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Teleost fish, such as Poecilia latipinna, exhibit remarkable regenerative capabilities, making them excellent models for studying tissue regrowth. They regenerate body parts like the tail fin through epimorphic regeneration, involving wound healing, blastema formation (a pool of proliferative cells), and tissue differentiation. Bone Morphogenetic Protein (BMP) and Fibroblast Growth Factor (FGF) signaling pathways play crucial roles in this process, but their specific functions during blastema formation remain unclear.

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Glassphalt suffers from performance defects, especially against moisture damage and fatigue cracking. In this research, the performance of glassphalt modified with CF has been evaluated against moisture damage, fatigue cracking and rutting. Based on this, Modified Lottman, Wilhelmy Plate (WP), Indirect Tensile Stiffness Modulus (ITSM), Indirect Tensile Fatigue (ITF), and Repeated Load Axial (RLA) tests have been performed on glassphalt modified with CF.

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