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Lettuce fortification through vitamin B-producing bacteria - proof of concept study.
J Sci Food Agric
January 2025
Center for Health & Bioresources, Bioresources Unit, AIT Austrian Institute of Technology, Tulln, Austria.
Background: Vitamin B (cobalamin) can be produced de novo only by certain bacteria and archaea. It plays a crucial role in the health of animals and humans, which obtain it only through diet, mainly from animal products. This study aimed to identify endophytic bacterial strains capable of synthesizing vitamin B and enriching edible plants with it as a potential solution for vitamin B deficiency in vegetarians, vegans, and people with poor diets.
View Article and Find Full Text PDFBackground: One-carbon metabolism (OCM), a biochemical pathway dependent on micronutrients including folate and vitamin B12, plays an essential role in aging-related physiological processes. DNA methylation-based aging biomarkers may be influenced by OCM.
Objective: This study investigated associations of OCM-related biomarkers with epigenetic aging biomarkers in the National Health and Nutrition Examination Survey (NHANES).
Friends and foes: symbiotic and algicidal bacterial influence on blooms.
ISME Commun
January 2025
Marine Microbiomics Laboratory, Biology Program, New York University Abu Dhabi, Abu Dhabi 129188, United Arab Emirates.
Harmful Algal Blooms (HABs) of the toxigenic dinoflagellate (KB) are pivotal in structuring the ecosystem of the Gulf of Mexico (GoM), decimating coastal ecology, local economies, and human health. Bacterial communities associated with toxigenic phytoplankton species play an important role in influencing toxin production in the laboratory, supplying essential factors to phytoplankton and even killing blooming species. However, our knowledge of the prevalence of these mechanisms during HAB events is limited, especially for KB blooms.
View Article and Find Full Text PDFUnlabelled: Vitamin B (cobalamin) is a high-value yet scarce cofactor required for various metabolic processes, making its efficient handling important for maintaining metabolic homeostasis. While the involvement of ATP:cob(I)alamin adenosyltransferases (MMAB) in the synthesis, delivery, and repair of 5'-deoxyadenosylcobalamin (AdoCbl) is well established, the kinetic mechanisms that regulate this process, particularly its negative cooperativity, remain poorly understood. Understanding these mechanisms is key to clarifying how MMAB efficiently uses AdoCbl, prevents resource wastage, and supports bacterial survival in nutrient-limited environments.
View Article and Find Full Text PDFCognitive disengagement syndrome: The same as or different from attention-deficit hyperactivity disorder? An examination based on biochemical parameters.
J Psychiatr Res
January 2025
Department of Child and Adolescent Psychiatry, Sakarya University Faculty of Medicine, Sakarya, Turkey.
Objectives: The aim of this study was to determine whether there are differences in the biochemical blood parameters between individuals with Cognitive Disengagement Syndrome (CDS) and Attention Deficit Hyperactivity Disorder (ADHD), and to investigate the relationship between vitamin levels and these disorders, as well as their impact on symptom severity.
Methods: The study included 35 patients with ADHD, 35 patients with both ADHD and CDS, and 35 healthy control subjects who presented to the child and adolescent psychiatry outpatient clinic between January 2022 and 2023, matched for age and gender. Children aged 7-15 were included in the study.
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