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Smartphone-Based Applications for Atrial Fibrillation Detection: A Systematic Review and Meta-Analysis of Diagnostic Test Accuracy.
Telemed J E Health
January 2025
Medical Department, Medical Sciences and Life School, Pontifical Catholic University of Goiás, Goiânia, Brazil.
Atrial fibrillation (AF) burden is strongly associated with an increased risk of stroke, which, in most cases, can be prevented through earlier detection of AF and the timely initiation of anticoagulation therapy. Smartphone devices can provide a simple, non-invasive, cost-effective early AF detection solution. PubMed, Embase, and Scopus databases were searched for studies comparing smartphone-based photoplethysmography (PPG) with standard electrocardiogram for AF detection.
View Article and Find Full Text PDFBackground: Obesity is a global health issue that complicates surgical outcomes, particularly in bariatric/metabolic surgery candidates. Assessing functional capacity is critical for optimizing preoperative planning and postoperative care. The Duke Activity Status Index (DASI) is a simple, self-administered questionnaire that estimates functional capacity based on daily activities.
View Article and Find Full Text PDFQuantitative methodology for poly (butylene adipate-co-terephthalate) (PBAT) microplastic detection in soil and compost.
Environ Sci Pollut Res Int
January 2025
Department of Packaging and Graphic Media Science, RIT, Rochester, NY, 14623, USA.
With the increasing use of biodegradable plastics in agriculture and food packaging, it has become increasingly important to assess the effects of their fragmentation and mineralization in the environment (i.e., soil, compost).
View Article and Find Full Text PDFEnantioselective Synthesis of α-Hydroxy Allyl Ketones via BINAP-CuH-Catalyzed Hydroacylation.
Angew Chem Int Ed Engl
January 2025
Indian Institute of Chemical Technology, Organic Synthesis and Process Chemistry, Uppal Road, 500607, Hyderabad, INDIA.
Catalytic hydrocupration of unsaturated carbon-carbon bonds to generate organometallic nucleophiles has recently become an attractive alternative to conventional stoichiometric reagents in the stereoselective synthesis. Herein, we have developed an efficient and economical method to synthesize enantiopure α-hydroxy allyl ketones via a copper hydride (CuH)-catalyzed hydroacylation of alkoxyallenes, a significant advancement given the scarcity of reports on such scaffolds in the literature. DFT calculations reveal that this reaction proceeds through the nucleophilic attack of a kinetically favourable Z-selective allyl-copper intermediate on acid anhydrides via a six-membered chair-like transition state, stabilized by strongly attractive non-covalent interactions that ultimately leads to high level of enantioselectivities using the simple BINAP ligand.
View Article and Find Full Text PDFFacile Fabrication of Injectable Multifunctional Hydrogels Based on Gallium-Polyphenol Networks with Superior Antibacterial Activity for Promoting Infected Wound Healing.
Adv Healthc Mater
January 2025
College of Biological Science and Engineering, Fuzhou University, Fuzhou, Fujian, 350108, China.
Multifunctional hydrogels hold significant promise for promoting the healing of infected wounds but often fall short in inhibiting antibiotic-resistant pathogens, and their clinical translation is limited by complex preparation processes and high costs. In this study, a multifunctional hydrogel is developed by combining metal-phenolic networks (MPNs) formed by tannic acid (TA) and gallium ions (Ga⁺) with chitosan (CS) through a simple one-step method. The resulting CS-TA-Ga⁺ (CTG) hydrogel is cost-effective and exhibits desirable properties, including injectability, self-healing, pH responsiveness, hemostasis, antioxidant, anti-inflammatory, and antibacterial activities.
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