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[Contribution and role of important biochemic factors in cerebral ischemia].
Pol Merkur Lekarski
March 2006
III Miejski Szpital w Lodzi, Oddział Rehabilitacji.
After an ischemic insult, a multi-faceted complex cascade of biochemical reactions occurs that ultimately causes neurons death. Above reactions exert an influence on: immunological changes (activation of the complement system and the generation of antibodies), increased inflammation (actions of proinflammatory cytokines and chemokines), the production of reactive oxygen species leading to oxidative stress, diminished mitochondrial function and activation of apoptotic pathways. There is also intensive release and wrong reversible escapement many of neurotransmitters.
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