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Plesiomonas shigelloides infection in newborn: case report and literature review.
Childs Nerv Syst
November 2024
NEUROFARBA Department, University of Florence, Florence, Italy.
Introduction: Plesiomonas shigelloides is a gram-negative bacillus causing foodborne infection due to contaminated seafood leading to gastroenteritis and dysentery. Instances of neonatal infection attributed to Plesiomonas shigelloides are exceedingly rare, and available literature is sparse, with only 15 reported cases to our knowledge. Central nervous system (CNS) involvement is reported, presenting severe meningoencephalitis in some cases.
View Article and Find Full Text PDFDr. Kiyoshi Shiga (1871-1957): Outstanding Bacteriologist Who Discovered Dysentery Bacillus and Contributed Immensely to Public Health in Japan.
Cureus
October 2024
Urogynecology, Yokosuka Urogynecology and Urology Clinic, Kanagawa, JPN.
Kiyoshi Shiga (1871-1957) was a renowned Japanese bacteriologist best known for discovering the dysentery bacillus. Born in Sendai during the Meiji Restoration, Shiga graduated from Tokyo Imperial University's School (later University of Tokyo) of Medicine and began microbiological research under Shibasaburo Kitasato. In 1897, during a dysentery () epidemic, he isolated and identified the causative organism (later named ) using Koch's postulates, laying the foundation for enteric disease research.
View Article and Find Full Text PDFModulating the antibacterial effect of the existing antibiotics along with repurposing drug metformin.
Arch Microbiol
March 2024
University of Rajshahi, Rajshahi, 6205, Bangladesh.
Owing to the extensive prevalence of resistant bacteria to numerous antibiotic classes, antimicrobial resistance (AMR) poses a well-known hazard to world health. As an alternate approach in the field of antimicrobial drug discovery, repurposing the available medications which are also called antibiotic resistance breakers has been pursued for the treatment of infections with antimicrobial resistance pathogens. In this study, we used Haloperidol, Metformin and Hydroxychloroquine as repurposing drugs in in vitro (Antibacterial Antibiotic Sensitivity Test and Minimum Inhibitory Concentration-MIC) and in vivo (Shigellosis in Swiss albino mice) tests in combination with traditional antibiotics (Oxytetracycline, Erythromycin, Doxycycline, Gentamicin, Ampicillin, Chloramphenicol, and Penicillin) against a group of AMR resistance bacteria (Bacillus cereus, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus, and Shigella boydii).
View Article and Find Full Text PDFComparative phytochemical study of methanolic and ethanolic extracts of Thymus linearis and their antibacterial and antioxidant potential.
Biomed Chromatogr
March 2024
Department of Chemistry, The University of Lahore, Lahore, Pakistan.
Thymus linearis (Thyme) is a medicinal plant widely distributed throughout Asia. Various parts of thyme are utilized for diverse medicinal purposes, including its use as a tonic and diuretic, for cough relief, as a flavoring agent, in treating dysentery, and for alleviating stomach disorders. Numerous studies have been conducted to explore the unexploited potential of thyme.
View Article and Find Full Text PDFOccurrence of shigellosis in pediatric diarrheal patients in Chattogram, Bangladesh: A molecular based approach.
PLoS One
June 2023
Department of Genetic Engineering & Biotechnology, Laboratory of Microbial & Cancer Genomics, University of Chittagong, Bangladesh.
Shigellaa Gram-negative, non-motile bacillus, is the primary causative agent of the infectious disease shigellosis, which kills 1.1 million people worldwideevery year. The children under the age of five are primarily the victims of this disease.
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