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Skeletal Muscle Relaxants and Their Impact on Intracranial Pressure in Neurosurgery.
Med Sci Monit
January 2025
Department of Rheumatology, University Clinical Hospital No. 1 Szczecin, Szczecin, Poland.
Skeletal muscle relaxants have their place in everyday use in numerous anesthesiological procedures, such as preparing a patient for surgery, supporting mechanical ventilation, and performing effective intubation. These drugs can be divided, based on their mechanism of action, into depolarizing skeletal relaxants, such as succinylcholine, and non-depolarizing skeletal muscle relaxants. Non-depolarizing agents are further categorized, based on their structure, into steroidal (eg, rocuronium) and benzylisoquinoline (eg, atracurium) compounds.
View Article and Find Full Text PDFRemimazolam Anesthesia for Modified Electroconvulsive Therapy Mitigates Postoperative Agitation.
Cureus
October 2024
Anesthesiology, Showa University Northern Yokohama Hospital, Yokohama, JPN.
Article Synopsis
- Postoperative complications like blood pressure spikes, agitation, and delirium can occur after modified electroconvulsive therapy (mECT), but remimazolam might help reduce these issues, despite limited reports on its use in this context.
- A 45-year-old man with severe depression and a history of postoperative agitation underwent mECT with remimazolam and suxamethonium, aiming for effective convulsions and a calm recovery.
- The patient displayed stable vital signs during the procedure and showed no postoperative agitation, suggesting that remimazolam could be beneficial, though its impact on convulsions during mECT needs further study.
Accidental Intrathecal Tranexamic Acid Injection During Caesarean Section: A Case Report.
Case Rep Anesthesiol
October 2024
Department of Obstetrics and Gynaecology, Muhimbili National Hospital, Dar es Salaam, Tanzania.
Tranexamic acid (TXA) is increasingly used in the management of haemorrhage during and after delivery and haemorrhage caused by other medical conditions due to its efficacy and safety. However, increasing report of fatal complications from inadvertent intrathecal TXA injection remains a cause of concern. The aim of this case report is to demonstrate clinical presentation and predictors of accidental intrathecal injection of TXA within the structure and processes of care in a health facility.
View Article and Find Full Text PDFAround anesthesia: anesthetic aspects of electroconvulsive treatment in the light of the latest reports - review article.
Psychiatr Pol
February 2024
Śląski Uniwersytet Medyczny w Katowicach, Wydział Nauk Medycznych w Katowicach Katedra i Klinika Psychiatrii Dorosłych.
Electroconvulsive therapy (ECT) remains the most effective method of treating acute mental conditions in psychiatry. The progress that has been made in anesthesiology in recent years allows for the personalization and optimization of electroconvulsive therapy through purely anesthetic interventions. There are few procedures in medicine where anesthesia would have such a direct impact on the effectiveness, or even success, of a given procedure.
View Article and Find Full Text PDFSuspected Pseudocholinesterase Deficiency During Left Thyroid Lobectomy and Isthmusectomy: A Case Report.
S D Med
June 2024
Avera Sacred Heart Hospital, Yankton, South Dakota.
Background: Pseudocholinesterase (butyrylcholinesterase) deficiency is an acquired or inherited condition in which decreased plasma levels of the pseudocholinesterase enzyme lead to an inability to metabolize the neuromuscular blocking agents succinylcholine and mivacurium, prolonging their paralytic effects. This often results in delayed extubation and additional intensive care requirements in the postoperative period.
Case Description: We describe a case of suspected pseudocholinesterase deficiency in a previously healthy 59-year-old female who underwent a left thyroid lobectomy and isthmusectomy.
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