AI Article Synopsis
- The use of a hexadeuterated internal standard significantly improved the assay of the marijuana carboxy metabolite in urine by enhancing the linearity of the procedure.
- Minimal chromatographic peak overlap between the internal standard and carboxy metabolite derivatives allowed for more accurate measurements.
- This reduction in peak overlap also enabled the same extract to be effectively analyzed using both ion trap detector and mass selective detector systems.
Article Abstract
The use of a hexadeuterated internal standard for the assay of the marijuana carboxy metabolite in urine resulted in two significant improvements. First, the linearity of the procedure was increased considerably because of the minimal chromatographic peak overlap of the internal standard and carboxy metabolite derivatives. Second, again because of minimal peak overlap, the same extract could be analyzed with similar results by both the ion trap detector and mass selective detector gas chromatograph/mass spectrometer systems.
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