An experimental study in pregnant mice shows no statistically significative teratogenic influence of ultrasounds.
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Life Sci Space Res (Amst)
February 2025
Gulhane School of Medicine, Department of Obstetrics and Gynecology, Ankara, Turkey.
Space missions have revealed certain disincentive factors of this unique environment, such as microgravity, cosmic radiation, etc., as the aerospace industry has made substantial progress in exploring deep space and its impacts on human body. Galactic cosmic radiation (GCR), a form of ionizing radiation, is one of those environmental factors that has potential health implications and, as a result, may limit the duration - and possibly the occurrence - of deep-space missions.
View Article and Find Full Text PDFPharmaceuticals (Basel)
January 2025
Departamento de Farmacia, Escuela Nacional de Ciencias Biológicas, Instituto Politécnico Nacional, Av. Wilfrido Massieu 399, Mexico City C.P. 07738, Mexico.
: In recent years the global incidence of cancer during pregnancy is rising, occurring in 1 out of every 1000 pregnancies. In this regard, the most used chemotherapy drugs to treat cancer are alkylating agents such as cyclophosphamide (Cp). Despite its great efficacy, has been associated with the production of oxidative stress and DNA damage, leading to embryotoxicity, genotoxicity, and teratogenicity in the developing .
View Article and Find Full Text PDFInt J Mol Sci
January 2025
Faculty of Pharmaceutical Sciences, University of Iceland, 107 Reykjavik, Iceland.
Exploring tazarotene, a third-generation retinoid for potential hand osteoarthritis treatment, this study presents the development and validation of an ultra-performance liquid chromatography with quadrupole detector mass spectrometry (UPLC-QDa) method for the simultaneous quantification of tazarotene and tazarotenic acid, its active metabolite, in porcine skin. Method development involved a design-of-experiments approach for chromatographic optimization of gradient steepness, organic solvent volume, column temperature, capillary voltage, flow rate, and cone voltage. Central composite orthogonal design was used to optimize peak area, peak width, retention time, and resolution.
View Article and Find Full Text PDFAntibiotics (Basel)
January 2025
Department of Health Sciences and The Water School, Florida Gulf Coast University, Fort Myers, FL 33965, USA.
This review investigates the levels of antibiotic residues in animal products, types of antibiotics, and their possible impact on human health in Africa. The literature search involved the use of a systematic survey using data that were published from Africa from 2015 to 2024. The search terms used the Boolean operators with keywords such as antibiotics, antibiotic residues, antibiotics in animal products in Africa, and impact on human health.
View Article and Find Full Text PDFBiology (Basel)
January 2025
Hunan Engineering Research Center of Ecological Environment Intelligent Monitoring and Disaster Prevention and Mitigation Technology in Dongting Lake Region, College of Information and Electronic Engineering, Hunan City University, Yiyang 413000, China.
Plant sterilants are used to control rodent populations due to their minimal environmental risk and other ethical considerations. However, their practical utilization is unsatisfactory due to high costs and processing difficulties. is a plant material that has shown the potential to inhibit the reproduction of , a species that causes serious damage to crops in the Dongting Lake region in China.
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