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Temporal properties of transcutaneous direct current motor conduction block.
J Neural Eng
January 2025
Physical Medicine and Rehabilitation, The MetroHealth System, 2500 Metrohealth Dr, Cleveland, OH 44109, USA, Cleveland, Ohio, 44109-1998, UNITED STATES.
Direct current (DC) electrical block of peripheral nerve conduction shows promise for clinical applications to treat spasticity, pain, and cardiac arrhythmias. Most previous work has used invasive nerve cuffs. Here we investigate the potential of non-invasive transcutaneous direct current motor block (tDCB).
View Article and Find Full Text PDFThe boost of force in unfused tetanic contractions at variable interpulse intervals in fast motor units of the rat medial gastrocnemius.
Sci Rep
January 2025
Department of Neurobiology, Poznan University of Physical Education, Poznan, Poland.
Previously, boost and sag effects seen in unfused tetanic contractions have been studied exclusively at constant stimulation frequency. However, intervals between successive discharges of motoneurons vary during voluntary movements. We therefore aimed to test whether the extra-efficient force production at the onset of contraction (boost) occurs during stimulation with variable intervals, and to what extent it depends on the level of interpulse interval (IPI) variability and history of stimulation.
View Article and Find Full Text PDFUsing Transcranial Magnetic Nerve Stimulation to Differentiate Motor and Sensory Fascicles in a Mixed Nerve: Experimental Rat Study.
J Reconstr Microsurg
January 2025
Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Taipei, Linkou, Chang Gung University, Taoyuan, Taiwan.
Background: Accurately matching the correct fascicles in a ruptured mixed nerve is critical for functional recovery. This study investigates the use of transcranial magnetic stimulation (TMS) to differentiate motor and sensory fascicles in a mixed nerve.
Methods: In all 40 rats, the median nerve in the left upper arm was evenly split into three segments.
Myotonia Congenita in Australian Merino Sheep with a Missense Variant in .
Animals (Basel)
December 2024
Sydney School of Veterinary Science, The University of Sydney, Camden, NSW 2570, Australia.
Myotonia congenita is a hereditary, non-dystrophic skeletal muscle disorder associated with muscle stiffness due to delayed muscle relaxation after contraction. We review myotonia congenita in domesticated animals and humans and investigated suspected myotonia congenita in a flock of Merino sheep in Australia. In 2020, a property in New South Wales reported a four-year history of lambs that would fall on disturbance before rapidly recovering, with 13 affected sheep identified in 2020.
View Article and Find Full Text PDFUtilizing Lateral Sprouting Axons to Reinnervate a Transferred Free Muscle to Enhance Distal Muscle Recovery When Performing High-Level Nerve Repair : Experimental Rat Study.
J Reconstr Microsurg
December 2024
Division of Reconstructive Microsurgery Department of Plastic and Reconstructive Surgery, Chang Gung Memorial Hospital, Taoyuan, Taiwan.
Background: High-level median or ulnar nerve injuries and repairs typically result in suboptimal re-innervation of distal muscles. Functioning Free Muscle Transplantation (FFMT) is increasingly recognized as an effective method to restore function in chronic muscle denervation cases. This study investigates the efficacy of using an additional FFMT, neurotized by lateral sprouting axons from a repaired high-level mixed nerve in the upper limb, to enhance distal hand function.
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