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Kaposiform hemangioendothelioma of infancy and childhood. An aggressive neoplasm associated with Kasabach-Merritt syndrome and lymphangiomatosis.
Am J Surg Pathol
April 1993
Department of Pathology, University of Michigan Medical Center, Ann Arbor 48109-0054.
We report the clinical and pathological features of nine distinctive, but relatively unknown, vascular tumors of infancy and childhood presenting as soft tissue masses often associated with locally aggressive disease, lymphangiomatosis and Kasabach-Merritt syndrome. The patients, four males and five females, were all in their first decade of life except for two (median, 2 years; range, 5 months to 19 years). These tumors involved deep soft tissues of the upper extremity (four cases), retroperitoneum (two cases), chest wall, scalp, and neck (one case each).
View Article and Find Full Text PDFGliosarcoma: a histologic and immunohistochemical reaffirmation.
Mod Pathol
January 1990
Henry Ford Hospital, Department of Pathology, Detroit, Michigan 48202.
Seven cases of mixed glioblastoma multiforme (GBM) and sarcoma, or gliosarcoma (GS) and six cases of GBM with a prominent pilocytic or spindle cell component were studied with a panel of ten antibodies using the ABC method. All 13 cases were originally diagnosed as GS based on hematoxylin and eosin- (H&E) and reticulin-stained sections. In all GS, the glial component stained strongly for glial fibrillary acidic protein (GFAP), and most stained for S-100 protein, while the sarcomatous areas of GS did not stain for either of these antigens.
View Article and Find Full Text PDFTufted angioma (angioblastoma). A benign progressive angioma, not to be confused with Kaposi's sarcoma or low-grade angiosarcoma.
J Am Acad Dermatol
February 1989
Institute of Dermatology, St. John's Hospital for Diseases of the Skin, London, England.
Twenty patients are described with an unusual form of angiomatous proliferation, which most commonly arose on the neck and upper trunk in young persons. Because of the histologic finding of small circumscribed angiomatous tufts and lobules scattered in the dermis, we suggest the term tufted angioma for this lesion. Over half the angiomas developed within the first 5 years of life, but only three patients reportedly had lesions at birth.
View Article and Find Full Text PDFHemangiosarcoma of the thyroid gland. Histological diagnosis problems.
Morphol Embryol (Bucur)
April 1984
A bleeding tumor of the thyroid gland in a 69-year-old woman is presented. Histologically, it was a hemangiosarcoma with proliferation and vessel neoformation: vascular-like clefts or distinct capillaries with tumoral endo- and perithelial structures were present. With reference to the published data, problems of differential diagnosis in the undifferentiated and giant cell carcinomas of the thyroid gland are discussed.
View Article and Find Full Text PDFThere are three principal malignant vasoformative tumors that can be found in the head and neck--hemangiopericytoma, angiosarcoma, and Kaposi's sarcoma. All are uncommon and provide challenges for the pathologist and the therapist both. The histogenesis of each tumor is different.
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