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Aerogels Based on Chitosan and Collagen Modified with FeO and FeO Nanoparticles: Fabrication and Characterization.
Polymers (Basel)
January 2025
Department of Engineering and Materials Science and Transportation, University of Seville, 41092 Seville, Spain.
The necessity to mitigate the intrinsic issues associated with tissue or organ transplants, in order to address the rising prevalence of diseases attributable to increased life expectancy, provides a rationale for the pursuit of innovation in the field of biomaterials. Specifically, biopolymeric aerogels represent a significant advancement in the field of tissue engineering, offering a promising solution for the formation of temporary porous matrices that can replace damaged tissues. However, the functional characteristics of these materials are inadequate, necessitating the implementation of matrix reinforcement methods to enhance their performance.
View Article and Find Full Text PDFDiabetes and Cataracts Development-Characteristics, Subtypes and Predictive Modeling Using Machine Learning in Romanian Patients: A Cross-Sectional Study.
Medicina (Kaunas)
December 2024
Second Department of Internal Medicine, "Victor Babes" University of Medicine and Pharmacy, 300041 Timisoara, Romania.
Diabetes has become a global epidemic, contributing to significant health challenges due to its complications. Among these, diabetes can affect sight through various mechanisms, emphasizing the importance of early identification and management of vision-threatening conditions in diabetic patients. Changes in the crystalline lens caused by diabetes may lead to temporary and permanent visual impairment.
View Article and Find Full Text PDFUnveiling the Mechanisms of a Remission in Major Depressive Disorder (MDD)-like Syndrome: The Role of Hippocampal Palmitoyltransferase Expression and Stress Susceptibility.
Biomolecules
January 2025
Research and Education Resource Center, Peoples Friendship University of Russia (RUDN University), 117198 Moscow, Russia.
Post-translational modifications of proteins via palmitoylation, a thioester linkage of a 16-carbon fatty acid to a cysteine residue, reversibly increases their affinity for cholesterol-rich lipid rafts in membranes, changing their function. Little is known about how altered palmitoylation affects function at the systemic level and contributes to CNS pathology. However, recent studies suggested a role for the downregulation of palmitoyl acetyltransferase (DHHC) 21 gene expression in the development of Major Depressive Disorder (MDD)-like syndrome.
View Article and Find Full Text PDFDisruption of boreal lake circulation in response to mid-Holocene warmth; evidence from the varved sediments of Lake Nautajärvi, southern Finland.
Sci Total Environ
January 2025
Department of Geography, Royal Holloway University of London, Surrey, UK.
Future climate projections are expected to have a substantial impact on boreal lake circulation regimes. Understanding lake sensitivity to warmer climates is therefore critical for mitigating potential ecological and societal impacts. The Holocene Thermal Maximum (HTM; ca 7-5 ka BP) provides a valuable analogue to investigate lake responses to warmer climates devoid of major anthropogenic influences.
View Article and Find Full Text PDFThe Effect of Surface Functionalization of Magnesium Alloy on Degradability, Bioactivity, Cytotoxicity, and Antibiofilm Activity.
J Funct Biomater
January 2025
Department of Pharmaceutical Science, University of Perugia, 06123 Perugia, Italy.
Magnesium alloys are promising biomaterials to be used as temporary implants due to their biocompatibility and biodegradability. The main limitation in the use of these alloys is their rapid biodegradation. Moreover, the risk of microbial infections, often following the implant surgery and hard to eradicate, is another challenge.
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