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Conventional ergonomic observation methods, such as rapid entire body assessment (REBA), are limited in their sensitivity and reliability, particularly in detecting changes in input variables. This study integrates fuzzy logic with the REBA method, utilizing trapezoidal membership functions to fuzzify the input variables. The center of gravity method was employed for defuzzification, and if-then rules were formulated to enhance the REBA method.

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Immersive gamma music as a tool for enhancing glymphatic clearance in astronauts while improving their mental well-being.

Life Sci Space Res (Amst)

February 2025

Studio Ozark Henry, Conterdijk 23, Wulpen, Belgium. Electronic address:

Spaceflight occurs under extreme environmental conditions that pose significant risks to the physical and mental health and well-being of astronauts. Certain factors, such as prolonged isolation, monotony, disrupted circadian rhythms, heavy workload, and weightlessness in space, can trigger psychological distress and may contribute to a variety of mental health problems, including mood and anxiety disturbances. Recent findings regarding spaceflight-associated alterations in cerebrospinal fluid spaces, demonstrating enlargement of the brain's perivascular spaces from preflight to postflight, at least suggest reduced glymphatic clearance in microgravity, and have raised concerns about long-term cognitive health in astronauts.

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Integrated spaceflight transcriptomic analyses and simulated space experiments reveal key molecular features and functional changes driven by space stressors in space-flown C. elegans.

Life Sci Space Res (Amst)

February 2025

Institute of Environmental Systems Biology, College of Environmental Science and Engineering, Dalian Maritime University, Dalian, 116026, Liaoning, PR China.

The space environment presents unique stressors, such as microgravity and space radiation, which can induce molecular and physiological changes in living organisms. To identify key reproducible transcriptomic features and explore potential biological roles in space-flown C. elegans, we integrated transcriptomic data from C.

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Functional and Structural Changes in the Inner Ear and Cochlear Hair Cell Loss Induced by Hypergravity.

Int J Mol Sci

January 2025

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Inha University, Incheon 22332, Republic of Korea.

Gravitational changes have been shown to cause significant abnormalities in various body systems, including the cardiovascular, immune, vestibular, and musculoskeletal systems. While numerous studies have examined the response of the vestibular system to gravitational stimulation, research on functional changes in the peripheral inner ear remains limited. The inner ear comprises two closely related structures: the vestibule and cochlea.

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High trade costs pose substantial barriers to the process of trade liberalization. This study aims to measure trade costs and explore the driving forces behind the growth of bilateral trade between Cambodia and its top 30 trading partners from 1993 to 2019. Using a micro-founded measure of trade costs derived from the gravity model, we find that Cambodia's average trade costs decreased by 35.

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